Technology Process of (S)-E-1-(3,4,5-trimethoxyphenyl)hept-1-en-4-yl-4-nitrobenzoate
There total 5 articles about (S)-E-1-(3,4,5-trimethoxyphenyl)hept-1-en-4-yl-4-nitrobenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 1h;
DOI:10.1039/c4ob00965g
- Guidance literature:
-
Multi-step reaction with 7 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 2 h / 0 - 20 °C
3: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C
4: ammonium molybdate tetrahydrate; dihydrogen peroxide / ethanol / 8 h / 0 - 20 °C
5: sodium hexamethyldisilazane / tetrahydrofuran / 3 h / 0 - 20 °C
6: hydrogenchloride / methanol; water / 2 h / 20 °C
7: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 1 h / 0 - 20 °C
With
hydrogenchloride; ammonium molybdate tetrahydrate; di-isopropyl azodicarboxylate; dihydrogen peroxide; sodium hexamethyldisilazane; N-ethyl-N,N-diisopropylamine; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water;
DOI:10.1039/c4ob00965g
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hexamethyldisilazane / tetrahydrofuran / 3 h / 0 - 20 °C
2: hydrogenchloride / methanol; water / 2 h / 20 °C
3: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 1 h / 0 - 20 °C
With
hydrogenchloride; di-isopropyl azodicarboxylate; sodium hexamethyldisilazane; triphenylphosphine;
In
tetrahydrofuran; methanol; water;
DOI:10.1039/c4ob00965g
