Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester
CAS No.:158040-49-4
Molecular Formula:C₄₄H₈₀O₇S₃Si₂
Molecular Weight:873.484
Hs Code.:

Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Synonyms:Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Suppliers and Price of Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

There total 7 articles about Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 69739-34-0
t-butyldimethylsiyl triflate

: 158040-48-3
Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-13-[1,3]dithian-2-yl-2,10-dihydroxy-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

: 158040-49-4
Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; Ambient temperature;
DOI:10.1016/S0040-4039(00)73331-4

Reference yield:

: 158040-44-9
Toluene-4-sulfonic acid (E)-(2S,6S,8S)-2-((S)-2,2-diisopropyl-[1,3]dioxolan-4-yl)-8-((2R,3S,5R,6S)-3,6-dimethoxy-5-methyl-tetrahydro-pyran-2-yl)-8-methoxy-4,6-dimethyl-oct-3-enyl ester

: 158040-49-4
Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 37 percent / CuCN / diethyl ether / 0 °C

2: 78 percent / BF₃*Et₂O / tetrahydrofuran / -78 deg C, 24 h, -50 deg C, 72 h

3: 65 percent / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature

4: 93 percent / 2,6-lutidine / CH₂Cl₂ / Ambient temperature

With 2,6-dimethylpyridine; dmap; boron trifluoride diethyl etherate; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1016/S0040-4039(00)73331-4

Reference yield:

: 158040-42-7
(2S,3S)-3-[(E)-(4S,6S)-6-((2R,3S,5R,6S)-3,6-Dimethoxy-5-methyl-tetrahydro-pyran-2-yl)-6-methoxy-2,4-dimethyl-hex-1-enyl]-butane-1,2,4-triol

: 158040-49-4
Toluene-4-sulfonic acid (E)-(2S,3R,7S,9S,10R,11S,13R)-3-allyl-2,10-bis-(tert-butyl-dimethyl-silanyloxy)-13-[1,3]dithian-2-yl-9,11-dimethoxy-5,7-dimethyl-tetradec-4-enyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 90 percent / TsOH / tetrahydrofuran / Ambient temperature

2: 95 percent / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature

3: 37 percent / CuCN / diethyl ether / 0 °C

4: 78 percent / BF₃*Et₂O / tetrahydrofuran / -78 deg C, 24 h, -50 deg C, 72 h

5: 65 percent / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature

6: 93 percent / 2,6-lutidine / CH₂Cl₂ / Ambient temperature

With 2,6-dimethylpyridine; dmap; boron trifluoride diethyl etherate; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1016/S0040-4039(00)73331-4