ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene

Base Information

• Chemical Name: ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene
• CAS No.: 869348-59-4
• Molecular Formula: C₂₀H₃₄O₂Si
• Molecular Weight: 334.574
• Mol file: 869348-59-4.mol

Synonyms:ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene

Chemical Property of ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene

There total 1 articles about ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(R)-1-benzyloxy-6-hepten-3-ol (869348-19-6) + tert-butyldimethylsilyl chloride (18162-48-6) → ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene (869348-59-4)

Guidance literature:

With 1H-imidazole; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; for 1h;

DOI:10.1021/ol051507n

Reference yield: 88.0%

ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene (869348-59-4) + methyl methacrylate (97-63-2,9003-42-3) → ethyl (R,E)-8-benzyloxy-6-tert-butyldimethylsilyloxy-2-methyl-2-octenoate (869348-60-7)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; for 5h; Heating;

DOI:10.1021/ol051507n

Reference yield: 67.0%

ethyl (R,E)-7-benzyloxy-5-tert-butyldimethylsilyloxy-1-heptene (869348-59-4) + C19H28O4 (1028224-68-1) → C37H58O6Si (1028224-80-7)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; Reflux;

DOI:10.1039/b719247a

upstream raw materials:

(R)-1-benzyloxy-6-hepten-3-ol

tert-butyldimethylsilyl chloride

Downstream raw materials:

ethyl (R,E)-8-benzyloxy-6-tert-butyldimethylsilyloxy-2-methyl-2-octenoate

ethyl (2S,3R,6R)-8-benzyloxy-6-tert-butyldimethylsilyloxy-2,3-dihydroxy-2-methyloctanoate

C₃₇H₅₈O₆Si