5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone

Base Information

• Chemical Name: 5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone
• CAS No.: 488829-39-6
• Molecular Formula: C₁₅H₁₂N₄OS
• Molecular Weight: 296.352
• Mol file: 488829-39-6.mol

Synonyms:5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone

Chemical Property of 5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone

There total 5 articles about 5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(E)-benzaldehyde hydrazone (41097-64-7) + (4Z)-2-(methylthio)-4-[(thiophen-2-yl)methylene]-1H-imidazol-5(4H)-one (280136-97-2) → 5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone (488829-39-6)

Guidance literature:

In ethanol; for 48h; Heating;

DOI:10.1080/10426500211714

Reference yield:

thiophene-2-carbaldehyde (98-03-3) → 5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone (488829-39-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: piperidine / ethanol / 12 h / 20 °C

2.1: aq. NaOH / methanol / 0.08 h / 20 °C

2.2: 92 percent / methanol; H₂O / 12 h / 20 °C

3.1: 78 percent / ethanol / 48 h / Heating

With piperidine; sodium hydroxide; In methanol; ethanol;

DOI:10.1080/10426500211714

Reference yield:

(5Z)-5-(thiophen-2-ylmethylene)-2-thioxoimidazolidin-4-one (280137-27-1) → 5-[(Z)-2-thienylidene]-2-((2-(E)-benzylidene)hydrazono)-4-imidazolidinone (488829-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: aq. NaOH / methanol / 0.08 h / 20 °C

1.2: 92 percent / methanol; H₂O / 12 h / 20 °C

2.1: 78 percent / ethanol / 48 h / Heating

With sodium hydroxide; In methanol; ethanol;

DOI:10.1080/10426500211714

upstream raw materials:

(E)-benzaldehyde hydrazone

(4Z)-2-(methylthio)-4-[(thiophen-2-yl)methylene]-1H-imidazol-5(4H)-one

thiophene-2-carbaldehyde

benzaldehyde