N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester

Base Information

Chemical Name:N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester
CAS No.:200293-66-9
Molecular Formula:C₂₇H₂₄N₂O₄S
Molecular Weight:472.565
Hs Code.:

Synonyms:N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester

Suppliers and Price of N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester

There total 3 articles about N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 203639-53-6
(R)-3-(1H-Indol-3-yl)-2-(4-iodo-benzenesulfonylamino)-propionic acid methyl ester

: 766-97-2
4-n-methylphenylacetylene

: 200293-66-9
N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1021/jm9707582

Reference yield:

: 98-61-3
p-Iodobenzenesulfonyl chloride

: 200293-66-9
N-[4-[2-(4-Methylphenyl)ethynyl]phenylsulfonyl]-D-tryptophan methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: N-methylmorpholine / CH₂Cl₂ / 2 h / Ambient temperature

2: Pd(PPh₃)2Cl₂, CuI, Et₃N / dimethylformamide / 50 °C

With 4-methyl-morpholine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm9707582