[2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Base Information

Chemical Name:[2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside
CAS No.:904691-65-2
Molecular Formula:C₃₉H₅₂N₂O₁₉S
Molecular Weight:884.91
Hs Code.:

[2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Synonyms:[2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Suppliers and Price of [2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

There total 11 articles about [2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 904691-58-3
[2-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylsulfanyl)-ethyl]-carbamic acid 2,2,2-trichloro-1,1-dimethyl-ethyl ester

: 904691-65-2
[2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 9 steps

1.1: 1.74 g / camphorsulfonic acid / acetonitrile / 20 °C

2.1: 77 percent / pyridine; DMAP / 24 h / cooling

3.1: acetic acid / H₂O / 4 h / 70 °C

4.1: 1.19 g / triethylamine / CH₂Cl₂ / 25.5 h / -20 - 20 °C

5.1: 2,6-di-tert-butyl-4-methylpyridine; molecular sieves 4 Angstroem / CH₂Cl₂ / 3 h / 20 °C

5.2: 76 percent / AgOTf / 2.5 h / cooling

6.1: ethylenediamine / ethanol; acetonitrile; tetrahydrofuran / 15 h / 80 °C

7.1: 247 mg / pyridine; DMAP / 24 h / cooling

8.1: AcOH; Zn / CH₂Cl₂ / 11 h / 20 °C

9.1: 179 mg / CH₂Cl₂ / 3 h

With pyridine; dmap; 2,6-di-tert-butyl-4-methylpyridine; 4 A molecular sieve; camphor-10-sulfonic acid; acetic acid; ethylenediamine; triethylamine; zinc; In tetrahydrofuran; ethanol; dichloromethane; water; acetonitrile;
DOI:10.1002/anie.200600591

Reference yield:

: acetic acid 3-acetoxy-5-hydroxy-6-hydroxymethyl-2-[2-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonylamino)-ethylsulfanyl]-tetrahydro-pyran-4-yl ester

: 904691-65-2
[2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1.1: 1.19 g / triethylamine / CH₂Cl₂ / 25.5 h / -20 - 20 °C

2.1: 2,6-di-tert-butyl-4-methylpyridine; molecular sieves 4 Angstroem / CH₂Cl₂ / 3 h / 20 °C

2.2: 76 percent / AgOTf / 2.5 h / cooling

3.1: ethylenediamine / ethanol; acetonitrile; tetrahydrofuran / 15 h / 80 °C

4.1: 247 mg / pyridine; DMAP / 24 h / cooling

5.1: AcOH; Zn / CH₂Cl₂ / 11 h / 20 °C

6.1: 179 mg / CH₂Cl₂ / 3 h

With pyridine; dmap; 2,6-di-tert-butyl-4-methylpyridine; 4 A molecular sieve; acetic acid; ethylenediamine; triethylamine; zinc; In tetrahydrofuran; ethanol; dichloromethane; acetonitrile;
DOI:10.1002/anie.200600591

Reference yield:

: 904691-59-4
1,1-dimethyl-2,2,2-trichloroethyl N-(2-mercaptoethyl)carbamate-(4,6-O-benzylidene)-1-thio-β-D-galactopyranoside

: 904691-65-2
[2-(methyl-4-carbamoylbutanoyl)ethyl] (3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-2,3-di-O-acetyl-6-O-benzoyl-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1.1: 77 percent / pyridine; DMAP / 24 h / cooling

2.1: acetic acid / H₂O / 4 h / 70 °C

3.1: 1.19 g / triethylamine / CH₂Cl₂ / 25.5 h / -20 - 20 °C

4.1: 2,6-di-tert-butyl-4-methylpyridine; molecular sieves 4 Angstroem / CH₂Cl₂ / 3 h / 20 °C

4.2: 76 percent / AgOTf / 2.5 h / cooling

5.1: ethylenediamine / ethanol; acetonitrile; tetrahydrofuran / 15 h / 80 °C

6.1: 247 mg / pyridine; DMAP / 24 h / cooling

7.1: AcOH; Zn / CH₂Cl₂ / 11 h / 20 °C

8.1: 179 mg / CH₂Cl₂ / 3 h

With pyridine; dmap; 2,6-di-tert-butyl-4-methylpyridine; 4 A molecular sieve; acetic acid; ethylenediamine; triethylamine; zinc; In tetrahydrofuran; ethanol; dichloromethane; water; acetonitrile;
DOI:10.1002/anie.200600591