Benzamide, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethyl-

Base Information

Chemical Name:Benzamide, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethyl-
CAS No.:74731-64-9
Molecular Formula:C16H21N5O3
Molecular Weight:331.3696
Hs Code.:
DSSTox Substance ID:DTXSID40225715
Nikkaji Number:J1.586.788D
Wikidata:Q83104823

Synonyms:BRN 6073151;Benzamide, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethyl-;74731-64-9;4-((2,4-Diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethylbenzamide;4-[(2,4-Diamino-5-pyrimidinyl)methyl]-2,6-dimethoxy-N,N-dimethylbenzamide;DTXSID40225715;C16H21N5O3;C16-H21-N5-O3;LS-26300

Suppliers and Price of Benzamide, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethyl-

Chemical Property:

Vapor Pressure:3.96E-17mmHg at 25°C
Boiling Point:656.8°C at 760 mmHg
Flash Point:351°C
Density:1.259g/cm³
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:331.16443955
Heavy Atom Count:24
Complexity:409

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC

Technology Process of Benzamide, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethyl-

There total 6 articles about Benzamide, 4-((2,4-diamino-5-pyrimidinyl)methyl)-2,6-dimethoxy-N,N-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 50-01-1
guanidine hydrochloride

: 74731-74-1
4-((Z)-2-Cyano-3-phenylamino-allyl)-2,6-dimethoxy-N,N-dimethyl-benzamide

: 74731-64-9
4-(2,4-Diamino-pyrimidin-5-ylmethyl)-2,6-dimethoxy-N,N-dimethyl-benzamide

Guidance literature:: With sodium methylate; In ethanol; for 40h; Heating;

Reference yield:

: 16849-70-0
4-methyl hydrogen 2,6-dimethoxyterephthalate

: 74731-64-9
4-(2,4-Diamino-pyrimidin-5-ylmethyl)-2,6-dimethoxy-N,N-dimethyl-benzamide

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / dimethylformamide / benzene / 2 h / Heating

2: 67 percent / CHCl₃ / 1 h / Ambient temperature

3: 71 percent / sodium bis(2-methoxyethoxy)aluminum hyride, morpholine / toluene / 4 h / -15 °C

4: 84 percent / sodium methylate / dimethylformamide / 0.25 h / 75 °C

5: 80 percent / propan-2-ol / 0.5 h / Heating

6: 66 percent / sodium methylate / ethanol / 40 h / Heating

With morpholine; thionyl chloride; sodium methylate; sodium bis(2-methoxyethoxy)aluminium dihydride; dimethylformamide; In ethanol; chloroform; N,N-dimethyl-formamide; isopropyl alcohol; toluene; benzene;

Reference yield:

: 74731-69-4
4-Formyl-2,6-dimethoxy-N,N-dimethyl-benzamide

: 74731-64-9
4-(2,4-Diamino-pyrimidin-5-ylmethyl)-2,6-dimethoxy-N,N-dimethyl-benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / sodium methylate / dimethylformamide / 0.25 h / 75 °C

2: 80 percent / propan-2-ol / 0.5 h / Heating

3: 66 percent / sodium methylate / ethanol / 40 h / Heating

With sodium methylate; In ethanol; N,N-dimethyl-formamide; isopropyl alcohol;