Amfetaminil

Base Information

• Chemical Name: Amfetaminil
• CAS No.: 17590-01-1
• Molecular Formula: C17H18N2
• Molecular Weight: 250.343
• Hs Code.: 2926909090
• European Community (EC) Number: 241-560-8
• NSC Number: 67172
• UNII: 0XU0V77JVE
• DSSTox Substance ID: DTXSID80864783
• Nikkaji Number: J9.101D
• Wikipedia: Amfetaminil
• Wikidata: Q474630
• NCI Thesaurus Code: C74237
• ChEMBL ID: CHEMBL2104064
• Mol file: 17590-01-1.mol

Synonyms:amphetaminil;amphetaminil, monohydrochloride;AN 1;AN-1;Aponeuron;N-(alpha-methylphenethyl)-2-phenylglycinonitrile

Chemical Property of Amfetaminil

Chemical Property:

• Appearance/Colour: White to Off-White Solid
• Vapor Pressure: 8.95E-07mmHg at 25°C
• Melting Point: 81-85 °C
• Refractive Index: 1.572
• Boiling Point: 405.167 °C at 760 mmHg
• PKA: 3.40±0.29(Predicted)
• Flash Point: 198.838 °C
• PSA: 35.82000
• Density: 1.062 g/cm³
• LogP: 3.86298
• Storage Temp.: Controlled Substance, -20?C Freezer
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 250.146998583
• Heavy Atom Count: 19
• Complexity: 292

Purity/Quality:

99%, ^*data from raw suppliers

AMFETAMINIL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC=CC=C1)NC(C#N)C2=CC=CC=C2

Technology Process of Amfetaminil

There total 3 articles about Amfetaminil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium cyanide (151-50-8) + amphetamine hydrochloride (2706-50-5,405-41-4) + benzaldehyde (100-52-7) → amphetaminil (17590-01-1)

Guidance literature:

DOI:10.1021/jm00292a042

Reference yield:

potassium cyanide (151-50-8) + benzaldehyde (100-52-7) + 2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2) → amphetaminil (17590-01-1)

Guidance literature:

Reference yield:

→ amphetaminil (17590-01-1)

Guidance literature:

Benzalaceton, Hydrazinhydrat, Benzaldehyd;

upstream raw materials:

potassium cyanide

amphetamine hydrochloride

benzaldehyde

2-amino-1-phenylpropane

Refernces