diethyl 2-acetamido-2-phenethyl-propanedioate

Base Information

Chemical Name:diethyl 2-acetamido-2-phenethyl-propanedioate
CAS No.:5463-92-3
Molecular Formula:C17H23NO5
Molecular Weight:321.373
Hs Code.:2924299090
NSC Number:20182
DSSTox Substance ID:DTXSID70281122
Wikidata:Q72434671
Mol file:5463-92-3.mol

Synonyms:Acetamino-phenethyl-malonsaeure-diethylester;Diethyl 2-acetamido-2-phenethylmalonate;2-acetylamino-2-phenylethylmalonic acid diethyl ester;Acetylamino-phenaethyl-malonsaeure-diaethylester;acetylamino-phenethyl-malonic acid diethyl ester;

Suppliers and Price of diethyl 2-acetamido-2-phenethyl-propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Diethyl (acetylamino)(2-phenylethyl)malonate >90%
1g
$ 540.00

Matrix Scientific
Diethyl (acetylamino)(2-phenylethyl)malonate >90%
500mg
$ 360.00

Crysdot
Diethyl2-acetamido-2-phenethylmalonate 95+%
1g
$ 513.00

American Custom Chemicals Corporation
DIETHYL-2-ACETAMIDO-2-PHENETHYLMALONATE 95.00%
5MG
$ 503.24

Alichem
Diethyl2-acetamido-2-phenethylmalonate
250mg
$ 215.25

AK Scientific
Diethyl2-acetamido-2-phenethylmalonate
1g
$ 779.00

AK Scientific
Diethyl2-acetamido-2-phenethylmalonate
500mg
$ 536.00

Total 27 raw suppliers

Chemical Property of diethyl 2-acetamido-2-phenethyl-propanedioate

Chemical Property:

Vapor Pressure:1.62E-09mmHg at 25°C
Melting Point:114-115oC
Boiling Point:483.8°C at 760 mmHg
Flash Point:246.4°C
PSA：81.70000
Density:1.132
LogP:2.01120
Storage Temp.:2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:321.15762283
Heavy Atom Count:23
Complexity:397

Purity/Quality:

97% ^*data from raw suppliers

Diethyl (acetylamino)(2-phenylethyl)malonate >90% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CCC1=CC=CC=C1)(C(=O)OCC)NC(=O)C
Uses Diethyl (Acetylamino)(2-phenylethyl)malonate is used perparation of 2-amino-2-[2-[4''-(2-ethyl-4-oxazolyl)[1,1''-biphenyl]-4-yl]ethyl]-1,3-propanediol.

Technology Process of diethyl 2-acetamido-2-phenethyl-propanedioate

There total 6 articles about diethyl 2-acetamido-2-phenethyl-propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.2%

: 103-63-9
1-phenyl-2-bromoethane

: 1068-90-2
2-acetylaminomalonic acid diethyl ester

: 5463-92-3
2-acetylamino-2-phenylethylmalonic acid diethyl ester

Guidance literature:: 2-acetylaminomalonic acid diethyl ester; With sodium; In ethanol; at 20 ℃; for 0.666667h;

1-phenyl-2-bromoethane; In ethanol; for 5h; Heating;
DOI:10.1080/10242430210706

Reference yield: 75.0%

: 17376-04-4
2-phenethyl iodide

: 1068-90-2
2-acetylaminomalonic acid diethyl ester

: 5463-92-3
2-acetylamino-2-phenylethylmalonic acid diethyl ester

Guidance literature:: 2-acetylaminomalonic acid diethyl ester; With sodium ethanolate; In ethanol; for 0.5h; Reflux;

2-phenethyl iodide; In ethanol; Reflux;
DOI:10.1021/jm200438b