(O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide

Base Information

• Chemical Name: (O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide
• CAS No.: 1384200-34-3
• Molecular Formula: C₁₅H₂₂FN₃O₅SSi
• Molecular Weight: 403.507
• Mol file: 1384200-34-3.mol

Synonyms:(O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide

Chemical Property of (O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide

There total 1 articles about (O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,1,3,3-tetramethyl-1,3-bis[N-methyl-N'-(4-nitrophenylsulfonyl)propylamidomethyl]-1,3-disiloxane (1375314-07-0) → (O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide (1384200-34-3)

Guidance literature:

With boron trifluoride diethyl etherate; In acetonitrile; for 2h; Reflux;

DOI:10.1021/om3002697

Reference yield: 89.0%

trimethylsilyl trifluoromethanesulfonate (27607-77-8) + (O->Si)chelate N'-(dimethylfluorosilylmethyl)-N'-methyl-N-nosyl-(R,S)-prolinamide (1384200-34-3) → N'-(dimethyltriflatosilylmethyl)-N-'methyl-N-(4-nitrobenzenesulfonyl)prolinamide

Guidance literature:

In benzene; for 3h; Reflux;

DOI:10.1007/s11172-019-2429-z

upstream raw materials:

1,1,3,3-tetramethyl-1,3-bis[N-methyl-N'-(4-nitrophenylsulfonyl)propylamidomethyl]-1,3-disiloxane