Technology Process of (R)-N,N-diisopropyl-3-phenyl-3-(5-formyl-2-triisopropylsilyloxyphenyl)propyl-1-amine
There total 6 articles about (R)-N,N-diisopropyl-3-phenyl-3-(5-formyl-2-triisopropylsilyloxyphenyl)propyl-1-amine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C31H48N2OSi;
With
diisobutylaluminium hydride;
In
hexane; dichloromethane;
at -5 - 0 ℃;
for 3h;
With
hydrogenchloride; water;
at 20 ℃;
for 1h;
With
sodium hydrogencarbonate;
In
diethyl ether; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1H-imidazole / 1,2-dichloro-ethane / 20 °C / Heating / reflux
2.1: diisobutylaluminium hydride / hexane; dichloromethane / 3 h / -5 - 0 °C
2.2: 1 h / 20 °C
With
1H-imidazole; diisobutylaluminium hydride;
In
hexane; dichloromethane; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydrogencarbonate / diethyl ether; water
2.1: 1H-imidazole / 1,2-dichloro-ethane / 20 °C / Heating / reflux
3.1: diisobutylaluminium hydride / hexane; dichloromethane / 3 h / -5 - 0 °C
3.2: 1 h / 20 °C
With
1H-imidazole; diisobutylaluminium hydride; sodium hydrogencarbonate;
In
diethyl ether; hexane; dichloromethane; water; 1,2-dichloro-ethane;
