[5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane

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Chemical Name:[5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane
CAS No.:1251469-42-7
Molecular Formula:C₂₈H₂₈Cl₂N₄O
Molecular Weight:507.463
Hs Code.:

Synonyms:[5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane

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Chemical Property of [5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane

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Technology Process of [5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane

There total 1 articles about [5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 123-75-1
pyrrolidine

: 1251469-34-7
ethyl 1-[3-((7-chloroquinolin-4-yl)amino)propyl]-2-methyl-5-(4-chlorophenyl)-1H-pyrrole-3-carboxylate

: 1251469-42-7
[5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane

Guidance literature:: pyrrolidine; With trimethylaluminum; In toluene; at 20 ℃; Cooling with ice; Inert atmosphere;

ethyl 1-[3-((7-chloroquinolin-4-yl)amino)propyl]-2-methyl-5-(4-chlorophenyl)-1H-pyrrole-3-carboxylate; In toluene; at 150 ℃; for 0.583333h; Microwave irradiation;
DOI:10.1016/j.bmc.2010.08.001

Reference yield: 38.0%

: 1251469-42-7
[5-(4-chlorophenyl)-1-(3-((7-chloroquinolin-4-yl)amino)-propyl)-2-methyl-1H-pyrrol-3-yl](pyrrolidin-1-yl)methane

: 1251469-47-2
7-chloro-4-[N-[3-(5-(4-chlorophenyl)-3-(pyrrolidin-1-ylmethyl)-2-methyl-1H-pyrrol-1-yl)propyl]amino]quinoline

Guidance literature:: With carbonylhydridetris(triphenylphosphine)rhodium(I); diphenylsilane; In tetrahydrofuran; for 5h; Reflux; Inert atmosphere;
DOI:10.1016/j.bmc.2010.08.001