Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl

Base Information

• Chemical Name: Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl
• CAS No.: 81657-27-4
• Molecular Formula: C₁₀₈H₁₂₆N₁₄O₂₃S₂
• Molecular Weight: 2052.4

Synonyms:Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl

Chemical Property of Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl

Chemical Property:

Purity/Quality:

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Technology Process of Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl

There total 1 articles about Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

H-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl + [(S)-1-({[(S)-1-((S)-1-Azidocarbonyl-ethylcarbamoyl)-2-hydroxy-propylcarbamoyl]-methyl}-carbamoyl)-ethyl]-carbamic acid tert-butyl ester → Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl (81657-27-4)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 4 ℃; for 12h;

DOI:10.1248/cpb.30.349

Reference yield: 16.0%

Z-Ala-Gly-Thr-Ala-Asp(OBzl)-Cys(MBzl)-Phe-Trp-Lys(Z)-Tyr-Cys(MBzl)-Val-OBzl (81657-27-4) → urotensin II, human (9047-55-6)

Guidance literature:

With ethylenediaminetetraacetic acid; trifluorormethanesulfonic acid; methyl-phenyl-thioether; In trifluoroacetic acid; for 1.5h;

DOI:10.1248/cpb.30.349

Downstream raw materials:

urotensin II, human

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