Technology Process of (R)-2-bromo-1-(3-bromophenyl)ethanol
There total 5 articles about (R)-2-bromo-1-(3-bromophenyl)ethanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
chloro([(S,2S)-(?)-2-amino-1,2-diphenylethyl](4-toluenesulfonyl)amido)(mesitylene)ruthenium (II); formic acid; [2,5-bis(2,6-diisopropylphenyl)cyclopent-3-en-1-yl]{1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methylsulfonamido}gold; water; triethylamine;
In
1,2-dichloro-ethane;
at 20 ℃;
for 14h;
enantioselective reaction;
DOI:10.1002/cctc.201500409
- Guidance literature:
-
With
[RhCl2(p-cymene)]2; (S,S,S)-CsDPEN; sodium formate; sodium dodecyl-sulfate;
In
water;
at 35 ℃;
for 8h;
optical yield given as %ee;
enantioselective reaction;
Inert atmosphere;
DOI:10.1016/j.tetasy.2011.04.017
- Guidance literature:
-
1-bromo-3-(2-bromoethyl)benzene;
With
escherichia coli (P450PL2-4) cells;
In
aq. phosphate buffer; ethanol;
at 35 ℃;
for 8h;
pH=8.5;
Green chemistry;
Enzymatic reaction;
With
cell-free extract of HheA10;
In
aq. phosphate buffer; ethanol;
at 35 ℃;
for 1h;
pH=8.5;
enantioselective reaction;
Enzymatic reaction;
Green chemistry;
DOI:10.1039/c9gc01802f
