methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate

Base Information

Chemical Name:methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate
CAS No.:1436415-46-1
Molecular Formula:C₂₃H₃₀O₈Si
Molecular Weight:462.572
Hs Code.:

Synonyms:methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate

Suppliers and Price of methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate

There total 2 articles about methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 201230-82-2
carbon monoxide

: 114605-46-8
methyl 2-iodo-3,5-dimethoxybenzoate

: 2-(tert-butyl-dimethyl-silanyloxymethyl)-5-trimethylstannanyl-pyran-4-one

: 1436415-46-1
methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate

Guidance literature:: With palladium diacetate; cesium fluoride; XPhos; In 1,4-dioxane; at 95 ℃; for 120h; under 3750.38 Torr;
DOI:10.1002/ejoc.201201256

Reference yield:

: 2150-37-0
methyl 3,5-dimethoxybenzoate

: 1436415-46-1
methyl 2-{6-[(tert-butyldimethylsilyloxy)methyl]-4-oxo-4H-pyran-3-carbonyl}-3,5-dimethoxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / acetonitrile / 7 h / Inert atmosphere; Reflux; Darkness

2: palladium diacetate; XPhos; cesium fluoride / 1,4-dioxane / 120 h / 95 °C / 3750.38 Torr

With N-iodo-succinimide; palladium diacetate; cesium fluoride; XPhos; In 1,4-dioxane; acetonitrile; 2: |Stille Carbonyl Synthesis;
DOI:10.1002/ejoc.201201256