Ethamidindole

Base Information

Chemical Name:Ethamidindole
CAS No.:72593-08-9
Molecular Formula:C24H27N5O2
Molecular Weight:417.51
Hs Code.:
DSSTox Substance ID:DTXSID00993443
Mol file:72593-08-9.mol

Synonyms:Ethamidindole;BRN 4596232;72593-08-9;1,4-Benzenedicarboxamide, N-(2-(3,4,6,7,12,12a-hexahydropyrazino(1',2':1,6)pyrido(3,4-b)indol-2-(1H)-yl)ethyl)-;DTXSID00993443;LS-29739;N~1~-[2-(3,4,6,7,12,12a-Hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-2(1H)-yl)ethyl]benzene-1,4-dicarboxamide

Suppliers and Price of Ethamidindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHAMIDINDOLE 95.00%
5MG
$ 498.83

Total 3 raw suppliers

Chemical Property of Ethamidindole

Chemical Property:

PSA：94.46000
LogP:2.70610
XLogP3:0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:417.21647512
Heavy Atom Count:31
Complexity:664

Purity/Quality:

99% ^*data from raw suppliers

ETHAMIDINDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CC3=C(CC2CN1CCNC(=O)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=C5N3

Technology Process of Ethamidindole

There total 4 articles about Ethamidindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.4%

: 72593-26-1
N-[2-(3,4,6,7,12,12a-Hexahydro-1H-pyrazino[1',2':1,6]pyrido[3,4-b]indol-2-yl)-ethyl]-terephthalamic acid ethyl ester

: 72593-08-9
Ethamidindole

Guidance literature:: With ammonia; In methanol; at 30 ℃; for 120h;

Reference yield:

: 91119-31-2
2-β-Aminoethyl-1,2,3,4,6,7,12,12a-octahydropyrazino<2',1':6,1>pyrido<3,4-b>indole

: 72593-08-9
Ethamidindole

Guidance literature:: Multi-step reaction with 2 steps

1: 66.6 percent / Et₃N / tetrahydrofuran / 1) 1h, 30 deg C, 2) 5h, reflux

2: 96.4 percent / NH₃ / methanol / 120 h / 30 °C

With ammonia; triethylamine; In tetrahydrofuran; methanol;

Reference yield:

: 91119-30-1
2-Cyanomethyl 1,2,3,4,6,7,12,12a-octahydropyrazino<2',1':6,1>pyrido<3,4-b>indol

: 72593-08-9
Ethamidindole

Guidance literature:: Multi-step reaction with 3 steps

1: 78.6 percent / LAH / tetrahydrofuran / 10 h / Heating

2: 66.6 percent / Et₃N / tetrahydrofuran / 1) 1h, 30 deg C, 2) 5h, reflux

3: 96.4 percent / NH₃ / methanol / 120 h / 30 °C

With lithium aluminium tetrahydride; ammonia; triethylamine; In tetrahydrofuran; methanol;