N-(4-butylphenyl)-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-9H-purin-2-amine hydrate (1:1)

Base Information

Chemical Name:N-(4-butylphenyl)-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-9H-purin-2-amine hydrate (1:1)
CAS No.:104715-74-4
Molecular Formula:C20H25 N5 O3
Molecular Weight:383.45
Hs Code.:

Synonyms:

Suppliers and Price of N-(4-butylphenyl)-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-9H-purin-2-amine hydrate (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-butylphenyl)-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-9H-purin-2-amine hydrate (1:1)

Chemical Property:

Vapor Pressure:1.66E-18mmHg at 25°C
Boiling Point:663.5°C at 760 mmHg
Flash Point:355°C

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(4-butylphenyl)-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-9H-purin-2-amine hydrate (1:1)

There total 6 articles about N-(4-butylphenyl)-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-9H-purin-2-amine hydrate (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 104715-73-3
2-(p-n-butylanilino)-6-chloro-9-(2-deoxy-β-D-ribofuranosyl)purine

: 104715-74-4
2-(p-n-butylanilino)-9-(2-deoxy-β-D-ribofuranosyl)purine

Guidance literature:: With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; water; for 4h; under 2585.7 Torr;
DOI:10.1021/jm00384a019

Reference yield:

: 104715-71-1
2-(p-n-butylanilino)-6-chloro-9-(2-deoxy-3,5-di-p-toluoyl-β-D-ribofuranosyl)purine

: 104715-74-4
2-(p-n-butylanilino)-9-(2-deoxy-β-D-ribofuranosyl)purine

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / MeONa / methanol / 24 h

2: 77 percent / K₂CO₃, H₂ / 10percent Pd/C / ethanol; H₂O / 4 h / 2585.7 Torr

With hydrogen; sodium methylate; potassium carbonate; palladium on activated charcoal; In methanol; ethanol; water;
DOI:10.1021/jm00384a019

Reference yield:

: 104-13-2
4-Butylaniline

: 104715-74-4
2-(p-n-butylanilino)-9-(2-deoxy-β-D-ribofuranosyl)purine

Guidance literature:: Multi-step reaction with 5 steps

1: 4-butylaniline hydrochloride / 2-methoxy-ethanol / Heating

2: 96 percent / phosphoryl chloride, N,N-dimethylaniline / 0.17 h / Heating

3: 1.) NaH / 1.) MeCN, RT, 20 min, 2.) MeCN, RT, 1 h

4: 76 percent / MeONa / methanol / 24 h

5: 77 percent / K₂CO₃, H₂ / 10percent Pd/C / ethanol; H₂O / 4 h / 2585.7 Torr

With hydrogen; sodium methylate; sodium hydride; potassium carbonate; p-butylaniline hydrochloride; N,N-dimethyl-aniline; trichlorophosphate; palladium on activated charcoal; In methanol; ethanol; 2-methoxy-ethanol; water;
DOI:10.1021/jm00384a019