Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide

Base Information

Chemical Name:Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide
CAS No.:129444-50-4
Molecular Formula:C₃₇H₃₀N₄O₅
Molecular Weight:610.669
Hs Code.:

Synonyms:Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide

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Chemical Property of Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide

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Technology Process of Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide

There total 1 articles about Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108833-14-3
((S)-5-Benzyloxy-8-methyl-1,2,3,6-tetrahydro-pyrrolo[3,2-e]indol-1-yl)-methanol

: 110314-42-6
5-(benzofuran-2-ylcarbonyl)amino-1H-indole-2-carboxylic acid

: 129444-50-4
Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide

Guidance literature:: With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; sodium bis(2-methoxyethoxy)aluminium dihydride; Multistep reaction; 1.) THF-toluene, 85 deg C;
DOI:10.1021/ja00256a041

Reference yield:

: 129444-50-4
Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-hydroxymethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide

: 110314-45-9
Benzofuran-2-carboxylic acid [2-((S)-5-benzyloxy-1-chloromethyl-8-methyl-1,6-dihydro-2H-pyrrolo[3,2-e]indole-3-carbonyl)-1H-indol-5-yl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine

2: lithium chloride / N,N-dimethyl-formamide / 80 - 100 °C

With pyridine; lithium chloride; In N,N-dimethyl-formamide;
DOI:10.1021/ja00256a041