(3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one

Base Information

• Chemical Name: (3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one
• CAS No.: 131617-19-1
• Molecular Formula: C₁₉H₂₈O₄
• Molecular Weight: 320.429

Synonyms:(3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one

Chemical Property of (3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one

There total 18 articles about (3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2S,3R,4S,5R)-1-O-benzyl-3,5-O-isopropylidene-2,4,6-trimethyl-6-heptene-1,3,5-triol (131589-20-3) → (3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one (131617-19-1)

Guidance literature:

With dimethylsulfide; ozone; In methanol; dichloromethane; 1.) -78 deg C; 2.) 0 deg C to 20 deg C, 10 h;

DOI:10.1016/S0040-4039(98)00691-1

Reference yield: 95.0%

methylmagnesium bromide (75-16-1) + (4R,5R,6R)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxane-4-carbonitrile (98315-34-5,98315-35-6) → 1-[(4S,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-ethanone (98315-28-7,131589-21-4,131617-19-1)

Guidance literature:

In tetrahydrofuran; diethyl ether; toluene; for 10h; Heating;

DOI:10.1016/S0040-4039(00)98954-8

Reference yield: 86.0%

(2S,3R,4S,5R,6S)-7-benzyloxy-3,5-isopropylidenedioxy-4,6-dimethyl-2-heptanol (863488-34-0) → (3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one (131617-19-1)

Guidance literature:

With sodium hydrogencarbonate; Dess-Martin periodane; In dichloromethane; at 0 ℃; for 24h;

DOI:10.1021/jo050792l

upstream raw materials:

(2S,3R,4S,5R)-1-O-benzyl-3,5-O-isopropylidene-2,4,6-trimethyl-6-heptene-1,3,5-triol

(2S,3R,4S,5R,6S)-7-benzyloxy-3,5-isopropylidenedioxy-4,6-dimethyl-2-heptanol

(2S,4R,5R,6S)-1-benzyloxy-6-(tert-butyldiphenylsilyloxy)-5-hydroxy-2,4-dimethyl-3-heptanone

(2S,3R,4S,5R,6S)-1-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxy)-2,4-dimethyl-heptane-3,5-diol

Downstream raw materials:

C₄₆H₇₄O₉SSi

1-[(4S,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2,5-trimethyl-[1,3]dioxan-4-yl]-3-hydroxy-3-methyl-pentane-1,4-dione

(2S,3R,4S,5R,6S,7R,10S,11R,12R,13R)-1,11-di-O-benzyl-13-O-(tert-butyldimethylsilyl)-2,4,6,8,10,12-hexamethyl-3,5-O-isopropylidene-7-(thiophenoxy)-8(E)-pentadecene-1,3,5,6,11,13-hexol

(2S,3R,4S,5R,6S,7S,10S,11R,12R,13R)-1,11-di-O-benzyl-13-O-(tert-butyldimethylsilyl)-2,4,6,8,10,12-hexamethyl-3,5-O-isopropylidene-7-(thiophenoxy)-8(E)-pentadecene-1,3,5,6,11,13-hexol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 131617-19-1 (3R,4S,5R,6S)-7-(benzyloxy)-3,5-(isopropylidenedioxy)-4,6-dimethylheptan-2-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send