1-Naphthalenemethanol

Base Information

• Chemical Name: 1-Naphthalenemethanol
• CAS No.: 4780-79-4
• Molecular Formula: C11H10O
• Molecular Weight: 158.2
• Hs Code.: 29062990
• European Community (EC) Number: 225-324-1
• NSC Number: 5315
• UNII: 4L2MEJ1Q34
• DSSTox Substance ID: DTXSID30197295
• Nikkaji Number: J215A
• Wikidata: Q27104433
• Metabolomics Workbench ID: 52213
• ChEMBL ID: CHEMBL1288
• Mol file: 4780-79-4.mol

Synonyms:1-naphthalenemethanol;1-naphthylmethanol

Chemical Property of 1-Naphthalenemethanol

Chemical Property:

• Appearance/Colour: yellowish fine crystalline powder
• Vapor Pressure: 0.000404mmHg at 25°C
• Melting Point: 61-63 °C(lit.)
• Refractive Index: 1.657
• Boiling Point: 303.6 °C at 760 mmHg
• PKA: 14.22±0.10(Predicted)
• Flash Point: 154 °C
• PSA: 20.23000
• Density: 1.151 g/cm³
• LogP: 2.33210
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: soluble in Methanol
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 158.073164938
• Heavy Atom Count: 12
• Complexity: 144

Purity/Quality:

99% ^*data from raw suppliers

1-Naphthalenemethanol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2CO
• Uses: 1-Naphthalenemethanol was used to investigate UV photooxidation of 1-methylnaphthalene in the presence of dry or humid air.

Technology Process of 1-Naphthalenemethanol

There total 110 articles about 1-Naphthalenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C23H26O2 → 1-naphthalene methanol (4780-79-4) + 4-phenyl-2-methyl-2-butanol (103-05-9)

Guidance literature:

With ammonium cerium (IV) nitrate; In water; acetone; at 0 - 20 ℃; for 121h; Reagent/catalyst;

DOI:10.1016/j.tetlet.2017.04.046

Reference yield: 100.0%

1-naphthylmethoxymethyl 3-phenylpropyl ether → 3-Phenyl-1-propanol (122-97-4) + 1-naphthalene methanol (4780-79-4)

Guidance literature:

In tetrahydrofuran; methanol; at 0 ℃; for 22h; Reflux;

DOI:10.1016/j.tetlet.2017.04.046

Reference yield: 95.0%

ethyl 1-naphthoate (3007-97-4) → 1-naphthalene methanol (4780-79-4)

Guidance literature:

With C₃₃H₂₉FeMnN₂O₃P; hydrogen; potassium carbonate; at 90 ℃; for 16h; under 37503.8 Torr; Autoclave;

DOI:10.1021/acs.orglett.8b00864

upstream raw materials:

methyl 1-naphthoate

1-naphthalenecarboxylic acid

naphthalen-1-ylmethyl acetate

1-naphthylcarboxamide

Downstream raw materials:

Chrysanthemumsaeure-

1-Fluoronaphthalene

1-naphthalenecarboxylic acid

1-Naphthylmethyl 4-methylphenylacetate

Refernces

• 1、 Hammond,Leermakers. "". . p. 207,208. Retrieved 1962.
• 2、 Zhu, Longfei,Ye, Sen,Wang, Jing,Zhu, Jiazheng,He, Guangke,Liu, Xiang. "Supported Iridium Catalyst for Clean Transfer Hydrogenation of Aldehydes and Ketones using Methanol as Hydrogen Source". . . Retrieved 2022/02/01.
• 3、 Wang, Jin,Ju, Ming-Yue,Wang, Xinghua,Ma, Yan-Na,Wei, Donghui,Chen, Xuenian. "Hydroboration Reaction and Mechanism of Carboxylic Acids using NaNH2(BH3)2, a Hydroboration Reagent with Reducing Capability between NaBH4and LiAlH4". . p. 5305 - 5316. Retrieved 2021/04/12.