(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

Base Information

Chemical Name:(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide
CAS No.:562870-88-6
Molecular Formula:C₂₀H₂₀F₃NO₂
Molecular Weight:363.38
Hs Code.:

Synonyms:(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

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Chemical Property of (R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

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Technology Process of (R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

There total 11 articles about (R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: (E)-2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid 5-phenyl-pent-2-enyl ester

: 562870-88-6
(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

Guidance literature:: With Proton Sponge; silver trifluoroacetate; chiral 2-ferrocenylimidazoline-based palladium complex; In dichloromethane; at 40 ℃; for 72h;
DOI:10.1002/anie.200601731

Reference yield: 98.0%

: 894777-25-4
2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid 5-phenyl-pent-2-enyl ester

: 562870-88-6
(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

Guidance literature:: With 4C₂F₃O₂^(1-)*2C₂₇H₂₂N₂O₂S^(2-)*2C₃₅H₂₅^(1-)*2Fe⁽²⁺⁾*2Pd⁽³⁺⁾; In dichloromethane; at 20 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja2098222

Reference yield: 93.0%

: 894777-25-4
2,2,2-trifluoro-N-(4-methoxyphenyl)acetimidic acid 5-phenyl-pent-2-enyl ester

: 562870-87-5
(S)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

: 562870-88-6
(R)-2,2,2-trifluoro-N-(4-methoxyphenyl)-N-(1-phenylethylallyl)acetamide

Guidance literature:: With [bis(μ-chloro[(R)-N,N-dimethyl(α-methylbenzyl)amino-2-C,N]palladium(II))]; Ag-(S)-TRIP; In chloroform; at 20 - 35 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere; Darkness;
DOI:10.1002/anie.201103843