ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate

Base Information

Chemical Name:ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate
CAS No.:1007583-09-6
Molecular Formula:C₁₅H₁₅BrN₂O₂S
Molecular Weight:367.266
Hs Code.:

Synonyms:ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate

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Chemical Property of ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate

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Technology Process of ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate

There total 4 articles about ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1559-02-0
diethyl cyclopropane-1,1-dicarboxylate

: 1007583-09-6
ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide; water / ethanol / 20 °C

2: diphenyl phosphoryl azide; triethylamine / 5 h / 20 °C / Heating / reflux

3: hydrogenchloride / ethyl acetate / 1 h / 20 °C

4: triethylamine / ethanol / 96 h / 65 °C

With hydrogenchloride; sodium hydroxide; diphenyl phosphoryl azide; water; triethylamine; In ethanol; ethyl acetate;

Reference yield:

: 3697-66-3
1,1-cyclopropanedicarboxylic acid monoethyl ester

: 1007583-09-6
ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: diphenyl phosphoryl azide; triethylamine / 5 h / 20 °C / Heating / reflux

2: hydrogenchloride / ethyl acetate / 1 h / 20 °C

3: triethylamine / ethanol / 96 h / 65 °C

With hydrogenchloride; diphenyl phosphoryl azide; triethylamine; In ethanol; ethyl acetate;

Reference yield:

: 107259-05-2
1-tert-butoxycarbonylamino-cyclopropanecarboxylic Acid Ethyl Ester

: 1007583-09-6
ethyl 1-{[4-(4-bromophenyl)-1,3-thiazol-2-yl]amino}cyclopropane carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / ethyl acetate / 1 h / 20 °C

2: triethylamine / ethanol / 96 h / 65 °C

With hydrogenchloride; triethylamine; In ethanol; ethyl acetate;