5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene

Base Information

• Chemical Name: 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene
• CAS No.: 328267-57-8
• Molecular Formula: C₃₃H₄₅N₃O₆
• Molecular Weight: 579.737

Synonyms:5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene

Chemical Property of 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene

There total 11 articles about 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.09,14]nonacosa-1(29),9(14),10,12,25,27-hexaene-16,23-dione (328267-56-7) → 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.09,14]nonacosa-1(29),9(14),10,12,25,27-hexaene (328267-57-8)

Guidance literature:

With tetrahydrofuran; borane; In tetrahydrofuran; for 2h; Heating;

DOI:10.1021/ja0284761

Reference yield: 40.0%

1,2-bis-(2-iodoethoxy)ethane (36839-55-1) + C27H35N3O4 (328267-55-6) → 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.09,14]nonacosa-1(29),9(14),10,12,25,27-hexaene (328267-57-8)

Guidance literature:

With potassium carbonate; In acetonitrile; for 96h; Reagent/catalyst; Solvent; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201403600

Reference yield:

1-bromo-2-(2'-nitro-5'-methylphenoxy)ethane (96315-07-0) → 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.09,14]nonacosa-1(29),9(14),10,12,25,27-hexaene (328267-57-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 55 percent / K₂CO₃; KI / acetonitrile / 60 h / Heating

2: 97 percent / H₂ / Pd/C / dimethylformamide / 18 h / 1672.11 Torr

3: 69 percent / triethylamine / CH₂Cl₂ / 28 h / 20 °C

4: 61 percent / borane/THF complex / tetrahydrofuran / 2 h / Heating

With tetrahydrofuran; borane; hydrogen; potassium carbonate; triethylamine; potassium iodide; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/ja0284761

upstream raw materials:

5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene-16,23-dione

2-nitro-5-methylphenol

3,6-dioxa-1,8-octanoyl dichloride

1-(2-methoxyethoxy)-2-nitro-benzene

Downstream raw materials:

C₃₉H₅₅N₃O₈

TAC-CHO

C₄₁H₅₆N₄O₁₀

TAC-NH₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 328267-57-8 5-[2-(2-methoxy-ethoxy)-phenyl]-11,28-dimethyl-2,8,18,21-tetraoxa-5,15,24-triaza-tricyclo[23.4.0.0^9,14]nonacosa-1⁽²⁹⁾,9⁽¹⁴⁾,10,12,25,27-hexaene

Send

Send

Metric Ton KG G Pound L ML

Send

Send