(Z)-1-Chloro-2-nonene

Base Information

• Chemical Name: (Z)-1-Chloro-2-nonene
• CAS No.: 67242-75-5
• Molecular Formula: C₉H₁₇Cl
• Molecular Weight: 160.687
• Mol file: 67242-75-5.mol

Synonyms:(Z)-1-chloronon-2-ene

Chemical Property of (Z)-1-Chloro-2-nonene

Chemical Property:

• Boiling Point: 200.4±9.0 °C(Predicted)
• Density: 0.882±0.06 g/cm3(Predicted)
• Solubility.: Chloroform

Purity/Quality:

99% ^*data from raw suppliers

(Z)-1-Chloro-2-nonene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (Z)-1-Chloro-2-nonene is an intermediate in the synthesis of Falcarinol (F101100), a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin.

Technology Process of (Z)-1-Chloro-2-nonene

There total 5 articles about (Z)-1-Chloro-2-nonene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(Z)-2-nonen-1-ol (41453-56-9) → (Z)-1-chloronon-2-ene (67242-75-5)

Guidance literature:

With 2,6-dimethylpyridine; methanesulfonyl chloride; lithium chloride; In N,N-dimethyl-formamide; at 10 ℃; Inert atmosphere;

DOI:10.1021/ol101646t

Reference yield: 89.0%

1-[(Z)-2-nonenyl]piperidine (97463-22-4) → N-Ethoxycarbonylpiperidine (5325-94-0) + (Z)-1-chloronon-2-ene (67242-75-5)

Guidance literature:

With chloroformic acid ethyl ester; In benzene;

Reference yield: 89.0%

chloroformic acid ethyl ester (541-41-3) + 1-[(Z)-2-nonenyl]piperidine (97463-22-4) → N-Ethoxycarbonylpiperidine (5325-94-0) + (Z)-1-chloronon-2-ene (67242-75-5)

Guidance literature:

In benzene; Product distribution; further solvent, further stereoisomer, further allylic tertiary amines, stereoisomeric purity of the double bond;

upstream raw materials:

chloroformic acid ethyl ester

1-[(Z)-2-nonenyl]piperidine

n-hexyllithium

(Z)-2-nonen-1-ol