2,5-Dibenzyl-3-hydroxy-6-methoxypyrazine

Base Information

Chemical Name:2,5-Dibenzyl-3-hydroxy-6-methoxypyrazine
CAS No.:132213-65-1
Molecular Formula:C₁₉H₁₈N₂O₂
Molecular Weight:306.364
Hs Code.:
UNII:L7EJN54CWT
DSSTox Substance ID:DTXSID801238175
Nikkaji Number:J737.781I
Wikidata:Q77571510
Metabolomics Workbench ID:102827

Synonyms:3,6-DBHM-pyrazine;3,6-dibenzyl-2-hydroxy-5-methoxypyrazine

Suppliers and Price of 2,5-Dibenzyl-3-hydroxy-6-methoxypyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,5-Dibenzyl-3-hydroxy-6-methoxypyrazine

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:306.136827821
Heavy Atom Count:23
Complexity:484

Purity/Quality:: 98.5% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(NC(=O)C(=N1)CC2=CC=CC=C2)CC3=CC=CC=C3

Technology Process of 2,5-Dibenzyl-3-hydroxy-6-methoxypyrazine

There total 5 articles about 2,5-Dibenzyl-3-hydroxy-6-methoxypyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 132213-64-0
2-acetoxy-3,6-dibenzyl-5-methoxypyrazine

: 132213-65-1
5-methoxy-3,6-bis(phenylmethyl)pyrazin-2-ol

Guidance literature:: With methanol; potassium carbonate; for 0.5h; Heating;
DOI:10.3987/COM-90-5479

Reference yield:

: 132213-61-7
3,6-dibenzyl-5-methoxypyrazine

: 132213-65-1
5-methoxy-3,6-bis(phenylmethyl)pyrazin-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / 60percent aq. H₂O₂, maleic anhydride / CHCl₃ / 12 h / Ambient temperature

2: 35 percent / 1.5 h / Heating

3: 99 percent / 10percent aq. K₂CO₃, MeOH / 0.5 h / Heating

With maleic anhydride; methanol; dihydrogen peroxide; potassium carbonate; In chloroform;
DOI:10.3987/COM-90-5479

Reference yield:

: 132213-60-6
3,6-dibenzyl-5-chloropyrazine

: 132213-65-1
5-methoxy-3,6-bis(phenylmethyl)pyrazin-2-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / methanol / 6 h / Heating

2: 95 percent / 60percent aq. H₂O₂, maleic anhydride / CHCl₃ / 12 h / Ambient temperature

3: 35 percent / 1.5 h / Heating

4: 99 percent / 10percent aq. K₂CO₃, MeOH / 0.5 h / Heating

With maleic anhydride; methanol; dihydrogen peroxide; potassium carbonate; In methanol; chloroform;
DOI:10.3987/COM-90-5479