Technology Process of 3,6-dibenzyl-2-benzyloxy-5-methoxypyrazine
There total 6 articles about 3,6-dibenzyl-2-benzyloxy-5-methoxypyrazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide; tetramethylammonium bromide;
In
chloroform;
at 30 ℃;
for 36h;
DOI:10.3987/COM-90-5479
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / 60percent aq. H2O2, maleic anhydride / CHCl3 / 12 h / Ambient temperature
2: 35 percent / 1.5 h / Heating
3: 99 percent / 10percent aq. K2CO3, MeOH / 0.5 h / Heating
4: 80 percent / 10percent aq. KOH, Me4NBr / CHCl3 / 36 h / 30 °C
With
maleic anhydride; methanol; potassium hydroxide; dihydrogen peroxide; tetramethylammonium bromide; potassium carbonate;
In
chloroform;
DOI:10.3987/COM-90-5479
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 35 percent / 1.5 h / Heating
2: 99 percent / 10percent aq. K2CO3, MeOH / 0.5 h / Heating
3: 80 percent / 10percent aq. KOH, Me4NBr / CHCl3 / 36 h / 30 °C
With
methanol; potassium hydroxide; tetramethylammonium bromide; potassium carbonate;
In
chloroform;
DOI:10.3987/COM-90-5479
