N-allyl-2,4,6-triisopropylbenzenesulfonamide

Base Information

• Chemical Name: N-allyl-2,4,6-triisopropylbenzenesulfonamide
• CAS No.: 1092224-00-4
• Molecular Formula: C₁₈H₂₉NO₂S
• Molecular Weight: 323.5
• Mol file: 1092224-00-4.mol

Synonyms:N-allyl-2,4,6-triisopropylbenzenesulfonamide

Chemical Property of N-allyl-2,4,6-triisopropylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-allyl-2,4,6-triisopropylbenzenesulfonamide

There total 1 articles about N-allyl-2,4,6-triisopropylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,4,6-triisopropylphenylsulfonyl chloride (6553-96-4) + 1-amino-2-propene (107-11-9,30551-89-4) → N-allyl-2,4,6-triisopropylbenzenesulfonamide (1092224-00-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jacs.1c04180

Reference yield: 52.0%

N-allyl-2,4,6-triisopropylbenzenesulfonamide (1092224-00-4) → 2-(iodomethyl)-1-((2,4,6-triisopropylphenyl)sulfonyl)aziridine

Guidance literature:

With iodine; chloroamine-T; In acetonitrile; at 20 ℃; for 19h; Inert atmosphere; Darkness;

DOI:10.1021/jacs.1c04180

Reference yield:

4-penten-3-one (1629-58-9) + N-allyl-2,4,6-triisopropylbenzenesulfonamide (1092224-00-4) → 1-(trans-4-methyl-1-(2,4,6-triisopropylphenylsulfonyl)pyrrolidin-3-yl)propan-1-one + 1-(cis-4-methyl-1-(2,4,6-triisopropylphenylsulfonyl)pyrrolidin-3-yl)propan-1-one

Guidance literature:

With chloro[2-(di-t-butylphosphino)biphenyl]gold; silver perchlorate; In toluene; at 90 ℃; for 20h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.3762/bjoc.7.126

upstream raw materials:

2,4,6-triisopropylphenylsulfonyl chloride

1-amino-2-propene