[(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol

Base Information

• Chemical Name: [(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol
• CAS No.: 185458-36-0
• Molecular Formula: C₁₄H₂₅O₄P₃
• Molecular Weight: 350.271
• Mol file: 185458-36-0.mol

Synonyms:[(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol

Chemical Property of [(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol

There total 3 articles about [(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + bis(2-phosphinoethyl)phenylphosphine (40392-45-8) → [(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol (185458-36-0)

Guidance literature:

In ethanol; water; at 25 ℃; for 2h;

Reference yield:

phenylphosphane (638-21-1) → [(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol (185458-36-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / t-BuOK / tetrahydrofuran / 0.5 h / Ambient temperature

2: 94 percent / LiAlH₄ / diethyl ether / 0 °C

3: 91 percent / ethanol; H₂O / 2 h / 25 °C

With lithium aluminium tetrahydride; potassium tert-butylate; In tetrahydrofuran; diethyl ether; ethanol; water;

Reference yield:

(2-{[2-(Diethoxy-phosphoryl)-ethyl]-phenyl-phosphanyl}-ethyl)-phosphonic acid diethyl ester (50964-54-0) → [(2-{[2-(Bis-hydroxymethyl-phosphanyl)-ethyl]-phenyl-phosphanyl}-ethyl)-hydroxymethyl-phosphanyl]-methanol (185458-36-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / LiAlH₄ / diethyl ether / 0 °C

2: 91 percent / ethanol; H₂O / 2 h / 25 °C

With lithium aluminium tetrahydride; In diethyl ether; ethanol; water;

upstream raw materials:

formaldehyd

bis(2-phosphinoethyl)phenylphosphine

(2-{[2-(Diethoxy-phosphoryl)-ethyl]-phenyl-phosphanyl}-ethyl)-phosphonic acid diethyl ester

phenylphosphane

Downstream raw materials:

PdCl(C₆H₅P(CH₂CH₂P(CH₂OH)2)2)⁽¹⁺⁾*Cl^(1-) = [PdCl(C₆H₅P(CH₂CH₂P(CH₂OH)2)2)]Cl

PtCl(C₆H₅P(CH₂CH₂P(CH₂OH)2)2)⁽¹⁺⁾*Cl^(1-) = [PtCl(C₆H₅P(CH₂CH₂P(CH₂OH)2)2)]Cl

[RhCl(C₆H₅P(CH₂CH₂P(CH₂OH)2)2)]