Menoctone

Base Information

Chemical Name:Menoctone
CAS No.:14561-42-3
Molecular Formula:C24H32 O3
Molecular Weight:368.516
Hs Code.:2914690090
NSC Number:103336
UNII:QP1A5BD6K9
DSSTox Substance ID:DTXSID60932651
Nikkaji Number:J8.509J
Wikidata:Q27287405
NCI Thesaurus Code:C81543
ChEMBL ID:CHEMBL1999063
Mol file:14561-42-3.mol

Synonyms:2-(8-cyclohexyloctyl)-3-hydroxy-1,4-naphthoquinone;menoctone;Win 11,530;WR 9808

Suppliers and Price of Menoctone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MENOCTONE 95.00%
5MG
$ 495.40

Total 4 raw suppliers

Chemical Property of Menoctone

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:519.3°Cat760mmHg
Flash Point:281.9°C
PSA：54.37000
Density:1.101g/cm³
LogP:6.57880
XLogP3:7.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:9
Exact Mass:368.23514488
Heavy Atom Count:27
Complexity:542

Purity/Quality:

99% ^*data from raw suppliers

MENOCTONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)CCCCCCCCC2=C(C3=CC=CC=C3C(=O)C2=O)O
Uses Antimalarial.

Technology Process of Menoctone

There total 15 articles about Menoctone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 3-(9-cyclohexylnonylidene)isochroman-1,4-dione

: 14561-42-3
2-hydroxy-3-(8-cyclohexyloctyl)-1,4-naphthoquinone

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 24h;
DOI:10.1128/AAC.00689-17

Reference yield:

: 16275-33-5
2-(3-phenylpropanoyl)cyclohexanone

: 14561-42-3
2-hydroxy-3-(8-cyclohexyloctyl)-1,4-naphthoquinone

Guidance literature:: Multi-step reaction with 4 steps

1: KOH

2: N₂H₄*H₂O

3: H₂ / PtO₂

4: (i) SOCl₂, (ii) H₂O₂, Py, (iii) /BRN= 1565260/, AcOH

With potassium hydroxide; hydrogen; hydrazine hydrate; platinum(IV) oxide;
DOI:10.1021/jm00316a001

Reference yield:

: 2270-20-4
5-Phenylpentanoic acid

: 14561-42-3
2-hydroxy-3-(8-cyclohexyloctyl)-1,4-naphthoquinone

Guidance literature:: Multi-step reaction with 6 steps

1: H₂ / Pt

2: LiAlH₄

3: HBr, H₂SO₄

4: (i), (ii) (hydrolysis), (iii) (decarboxylation)

6: (i) SOCl₂, (ii) H₂O₂, Py, (iii) /BRN= 1565260/, AcOH

With lithium aluminium tetrahydride; sulfuric acid; hydrogen bromide; hydrogen; platinum;
DOI:10.1021/jm00316a001