methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate

Base Information

Chemical Name:methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate
CAS No.:886042-58-6
Molecular Formula:C₂₇H₃₂N₂O₄
Molecular Weight:448.562
Hs Code.:

Synonyms:methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate

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Chemical Property of methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate

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Technology Process of methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate

There total 1 articles about methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 886042-57-5
methyl 3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-2-{2-[(hydroxyimino)methyl]phenyl}-1H-indole-6-carboxylate

: 886042-58-6
methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate

Guidance literature:: With hydrogen; acetic acid; platinum(IV) oxide; for 48h; under 2585.81 Torr;

Reference yield: 46.0%

: 886042-58-6
methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate

: 886042-59-7
methyl 14-cyclohexyl-5,6,7,8-tetrahydroindolo[2,1-a][2,5]benzodiazocine-11-carboxylate

Guidance literature:: methyl2-[2-(aminomethyl)phenyl]-3-cyclohexyl-1-(1,3-dioxolan-2-ylmethyl)-1H-indole-6-carboxylate; With hydrogenchloride; water; In tetrahydrofuran; for 24h; Heating / reflux;

With acetic acid; In methanol; for 0.333333h; pH=4;

With water; sodium cyanoborohydride; sodium hydrogencarbonate; more than 3 stages;