4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

Base Information

Chemical Name:4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline
CAS No.:1376615-33-6
Molecular Formula:C₁₉H₁₈ClN₃
Molecular Weight:323.825
Hs Code.:

Synonyms:4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

Suppliers and Price of 4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

There total 6 articles about 4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 168079-19-4
10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

: 1376615-33-6
4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

Guidance literature:: 10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine; With borane-THF; In tetrahydrofuran; at 20 ℃; for 18h;

With water; In tetrahydrofuran; for 0.25h;

Reference yield:

: 1003-29-8,254729-95-8
2-pyrrole aldehyde

: 1376615-33-6
4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide

2.1: hydrogen / palladium on activated charcoal

3.1: triethylamine / dichloromethane

4.1: ammonium chloride; iron / ethanol; water

5.1: borane-THF / tetrahydrofuran / 18 h / 20 °C

5.2: 0.25 h

With borane-THF; hydrogen; iron; sodium hydride; ammonium chloride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 22162-51-2
1-(2-Nitrobenzyl)-2-pyrrolecarboxaldehyde

: 1376615-33-6
4-((5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10(11H)-yl)methyl)-3-chloroaniline

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogen / palladium on activated charcoal

2.1: triethylamine / dichloromethane

3.1: ammonium chloride; iron / ethanol; water

4.1: borane-THF / tetrahydrofuran / 18 h / 20 °C

4.2: 0.25 h

With borane-THF; hydrogen; iron; ammonium chloride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; water;