10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

Base Information

Chemical Name:10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine
CAS No.:168079-19-4
Molecular Formula:C₁₉H₁₆ClN₃O
Molecular Weight:337.809
Hs Code.:

Synonyms:10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

Suppliers and Price of 10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

Chemical Property:

Boiling Point:607.4±55.0 °C(Predicted)
Density:1.35±0.1 g/cm3(Predicted)

Purity/Quality:: 95%-98% ^*data from raw suppliers

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Technology Process of 10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

There total 8 articles about 10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 179063-21-9
(2-chloro-4-nitrophenyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl-methanone

: 168079-19-4
10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In N,N-dimethyl-formamide; at 35 - 40 ℃; for 6h; Solvent;
DOI:10.1002/jhet.2176

Reference yield:

: 179063-21-9
(2-chloro-4-nitrophenyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-yl-methanone

: 168079-19-4
10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

Guidance literature:: With sodium hydrogencarbonate; In ethanol;

Reference yield:

: 22162-53-4
10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepine

: 168079-19-4
10,11-Dihydro-10-(2-chloro-4-aminobenzoyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine

Guidance literature:: Multi-step reaction with 2 steps

2: H₂ / Pd/C

With hydrogen; palladium on activated charcoal;
DOI:10.1021/jm980179c