4-Nitrophthalhydrazide

Base Information

• Chemical Name: 4-Nitrophthalhydrazide
• CAS No.: 3682-19-7
• Molecular Formula: C8H5N3O4
• Molecular Weight: 207.145
• Hs Code.: 2933990090
• NSC Number: 9339
• DSSTox Substance ID: DTXSID1025774
• Nikkaji Number: J265.513F
• ChEMBL ID: CHEMBL1870887
• Mol file: 3682-19-7.mol

Synonyms:4-Nitrophthalhydrazide;3682-19-7;6-nitro-2,3-dihydrophthalazine-1,4-dione;6-NITROPHTHALHYDRAZIDE;4-Nitrophthalic Hydrazide;6-nitrophthalazine-1,4-diol;CCRIS 4683;1,4-Phthalazinedione, 2,3-dihydro-6-nitro-;NSC 9339;N-Amino-4-nitrophthalimide;BRN 0218329;MLS002152890;MLS002638084;DTXSID1025774;SMR001224502;NSC9339;2,3-Dihydro-6-nitro-1,4-phthalazinedione;Cambridge id 5214515;Oprea1_716875;CBDivE_006628;SCHEMBL895627;DTXCID605774;CHEMBL1870887;BDBM74249;cid_3543259;HMS3039A12;HMS3087O24;LS-99;1,4-Dihydroxy-6-nitro-phthalazine;NSC-9339;Tox21_200021;MFCD00006891;STK359427;STL432878;STL512032;AKOS000280999;AKOS000435801;AKOS015916645;AKOS037491483;CCG-245317;4-hydroxy-7-nitrophthalazin-1(2H)-one;NCGC00091569-01;NCGC00091569-02;NCGC00257575-01;AS-64535;SMR001547577;CAS-3682-19-7;6-nitro-2,3-dihydrophthalazine-1,4-quinone;CS-0089653;FT-0619293;N0799;6-Nitro-2,3-dihydro-1,4-phthalazinedione #;D74894;AB00075468-01;6-Nitro-1.4-dioxo-1.2.3.4-tetrahydrophthalazin;A823384;SR-01000198838;6-nitro-1,2,3,4-tetrahydrophthalazine-1,4-dione;SR-01000198838-1;METHYL-1-BENZYL-4-METHYL-PYRROLIDINE-3-CARBOXYLATE

Chemical Property of 4-Nitrophthalhydrazide

Chemical Property:

• Appearance/Colour: light yellow powder
• Vapor Pressure: 2.65E-16mmHg at 25°C
• Melting Point: 300°C(dec.)(lit.)
• Refractive Index: 1.628
• Boiling Point: 626.8 °C at 760 mmHg
• PKA: 9.30±0.20(Predicted)
• Flash Point: 332.9 °C
• PSA: 111.54000
• Density: 1.555g/cm³
• LogP: 0.64780
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 207.02800565
• Heavy Atom Count: 15
• Complexity: 324

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Nitrophthalhydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1[N+](=O)[O-])C(=O)NNC2=O

Technology Process of 4-Nitrophthalhydrazide

There total 10 articles about 4-Nitrophthalhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-nitrophthalic anhydride (5466-84-2) → 6-nitro-2,3-dihydrophthalazine-1,4-dione (3682-19-7)

Guidance literature:

With hydrazine; In water; acetic acid; at 120 ℃; for 2h;

Reference yield: 80.0%

4-nitrophthalimide (89-40-7) → 6-nitro-2,3-dihydrophthalazine-1,4-dione (3682-19-7)

Guidance literature:

With hydrazine hydrate; In ethanol; for 5h; Reflux;

Reference yield: 72.0%

4-nitrophthalic anhydride (5466-84-2) → 1,4-dihydroxy-6-nitro-phthalazine (3682-19-7)

Guidance literature:

4-nitrophthalic anhydride; With hydrazine; In isopropyl alcohol; at 85 ℃; for 5h;

With hydrogenchloride; water; In isopropyl alcohol; pH=3;

upstream raw materials:

4-nitrophthalic anhydride

4-nitrophthalic acid

4-nitrophthalimide

5-nitro-3H-isobenzofuran-1-one

Downstream raw materials:

isoluminol

4-nitrophthalic acid

hydrazine

1-Chloro-4-(3-chloro-4-methoxybenzyl)amino-6-nitrophthalazine

Refernces

• 1、 -. "Luminol or isoluminol synthesizing method by one-pot process". . . Retrieved 2017/08/30.
• 2、 -. "PHTHALAZINE DERIVATIVES". Page/Page column 53. . Retrieved 2008/12/05.