Amiprofos-methyl

Base Information

• Chemical Name: Amiprofos-methyl
• CAS No.: 36001-88-4
• Deprecated CAS: 55840-20-5
• Molecular Formula: C11H17 N2 O4 P S
• Molecular Weight: 304.307
• Hs Code.: 2929909011
• European Community (EC) Number: 252-829-4
• NSC Number: 313446
• UNII: D130E8V1ON
• DSSTox Substance ID: DTXSID4041600
• Nikkaji Number: J1.889I
• Wikidata: Q27275963
• ChEMBL ID: CHEMBL1256629
• Mol file: 36001-88-4.mol

Synonyms:amiprophos methyl

Chemical Property of Amiprofos-methyl

Chemical Property:

• Melting Point: ~65 °C
• Refractive Index: 1.553
• Boiling Point: 389.9°Cat760mmHg
• Flash Point: 189.6°C
• PSA: 118.21000
• Density: 1.275g/cm³
• LogP: 4.71560
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 304.06466520
• Heavy Atom Count: 19
• Complexity: 361

Purity/Quality:

98%,99%, ^*data from raw suppliers

Amiprofos methyl PESTANAL , analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)OP(=S)(NC(C)C)OC)[N+](=O)[O-]
• Description: Amiprofos-methyl (APM) is a phosphoric amide herbicide. It reversibly decreases H. vulgare root and shoot length and inhibits in vitro polymerization of Rosa tubulin induced by paclitaxel in a dose-dependent manner. APM completely inhibits tubulin polymerization in Hemanthus endosperm cells at a concentration of 0.1 μM. The antitubulin effects of APM are specific to plants as it has no effect on bovine brain tubulin polymerization at concentrations up to 100 μM. APM inhibits calcium accumulation in corn mitochondria (ID50 = 140 nM) and induces a 3-fold increase in the rate of calcium efflux from rat liver mitochondria at a concentration of 100 nM. APM inhibits the growth of P. falciparum (IC50 = 3.5 μM) and completely inhibits microtubule polymerization in P. falciparum trophozoites at a concentration of 20 μM.
• Uses: Amiprofos-methyl is useful in herbicide compositions.

Technology Process of Amiprofos-methyl

There total 1 articles about Amiprofos-methyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ O-methyl O-(2-nitro-p-tolyl)-N-isopropylphosphoramidothionate (36001-88-4)

Guidance literature:

Refernces