pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

Base Information

• Chemical Name: pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside
• CAS No.: 215794-86-8
• Molecular Formula: C₂₆H₂₈N₂O₅S
• Molecular Weight: 480.585
• Mol file: 215794-86-8.mol

Synonyms:pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

Chemical Property of pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside

There total 1 articles about pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,2-O-(1-methoxyethylidene)-3,4-di-O-benzyl-β-L-rhamnopyranose (72657-01-3) + 2-sulfanylpyrimidine (131242-36-9) → pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside (215794-86-8)

Guidance literature:

With mercury dibromide; In acetonitrile; for 0.5h; Heating;

DOI:10.1016/S0008-6215(98)00164-5

Reference yield: 95.0%

pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside (215794-86-8) + 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose (4064-06-6) → O-(2-O-acetyl-3,4-di-O-benzyl-6-deoxy-α-L-mannopyranosyl)-(1->6)-1,2;3,4-di-O-isopropylidene-α-D-galactopyranose

Guidance literature:

With 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; for 0.5h; Ambient temperature;

DOI:10.1016/S0008-6215(98)00164-5

Reference yield: 65.0%

pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-L-rhamnopyranoside (215794-86-8) + 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose (4064-06-6) → O-(2-O-acetyl-3,4-di-O-benzyl-6-deoxy-α-L-mannopyranosyl)-(1->6)-1,2;3,4-di-O-isopropylidene-α-D-galactopyranose + benzyl 2-O-acetyl-3,4-di-O-benzyl-α-L-rhamnopyranoside (215794-96-0)

Guidance literature:

With 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; for 0.5h; Product distribution; Ambient temperature; different sugars, promoter quantities and reaction times;

DOI:10.1016/S0008-6215(98)00164-5

upstream raw materials:

1,2-O-(1-methoxyethylidene)-3,4-di-O-benzyl-β-L-rhamnopyranose

2-sulfanylpyrimidine

Downstream raw materials:

benzyl 2-O-acetyl-3,4-di-O-benzyl-α-L-rhamnopyranoside