131242-36-9Relevant articles and documents
High-purity 2-pyrimidinethiol preparation method and 2-pyrimidinethiol prepared by same
-
Paragraph 0045-0051, (2017/12/30)
The invention provides a high-purity 2-pyrimidinethiol preparation method which includes the steps: (1) adding and dissolving reactant 2-chloro-pyrimidine and sulfides into solvents according to the molar ratio of 1:1, adding compound catalysts, controlling reaction temperature to react mixture, and tracking reaction by thin-layer chromatography until the 2-chloro-pyrimidine completely reacts; (2) cooling mixture to reach indoor temperature after reaction, separating out yellow tabular crystals and then performing suction filtration; (3) washing the yellow tabular crystals by water, performing recrystallization on the yellow tabular crystals by the aid of mixed solvents, and filtering and drying mixture to obtain high-purity 2-pyrimidinethiol. Reaction solvents and compound catalysts in the preparation process of the 2-pyrimidinethiol can be repeatedly used, production cost can be reduced, environmental pollution is reduced, continuous production time is saved, and manpower and material resources are saved. The high-purity 2-pyrimidinethiol prepared by the preparation method is low in production cost, good in purity, high in yield, less in environmental pollution and safer to produce, and the yield of the 2-pyrimidinethiol can reach 92.8%.
Modified Borohydride Agents, 1-Benzyl-4-aza-1-azoniabicyclooctane Tetrahydroborate (BAAOTB) versus Tetrabutylammonium Tetrahydroborate (TBATB). Efficient, Selective, and Versatile Reducing Agents
Firouzabadi, Habib,Afsharifar, Gholam Reza
, p. 2595 - 2602 (2007/10/03)
1-Benzyl-4-aza-1-azoniabicyclooctane tetrahydroborate (BAAOTB) and tetrabutylammonium tetrahydroborate (TBATB) are used for the selective reductions of aldehydes, ketones, α,β-unsaturated carbonyl compounds, acid chlorides, azides, epoxides, and disulfides in t-BuOH and hexane/chloroform.ABBOAB with its rigid and bulky structure reacts more selectively than its analogue TBATB.
CONDITIONAL EQUILIBRIUM CONSTANT OF THE REACTION OF 2-MERCAPTOPYRIMIDINE WITH IODINE IN ACIDIC SOLUTION
Kurzawa, Jan,Janowicz, Krystyna
, p. 147 - 156 (2007/10/02)
The reaction of 2-mercaptopyrimidine with iodine in HClO4 solution has been investigated.Conditional equilibrium constant was calculated from the known initial concentrations of 0, 0 and from the equilibrium concentration of determined by spectrophotometry.The conditional equilibrium constant in 1 M HClO4 is 307+/-24, and in 2 M HClO4 is 20+/-1.
