(R)-α-octyl deoxybenzoin

Base Information

• Chemical Name: (R)-α-octyl deoxybenzoin
• CAS No.: 1418731-62-0
• Molecular Formula: C₂₂H₂₈O
• Molecular Weight: 308.464
• Mol file: 1418731-62-0.mol

Synonyms:(R)-α-octyl deoxybenzoin

Chemical Property of (R)-α-octyl deoxybenzoin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-α-octyl deoxybenzoin

There total 11 articles about (R)-α-octyl deoxybenzoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H30O (1418731-59-5) → (R)-α-octyl deoxybenzoin (1418731-62-0)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 0.75h;

DOI:10.1021/jo3023928

Reference yield:

α-propyl deoxybenzoin (21383-02-8) → (R)-α-octyl deoxybenzoin (1418731-62-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: RuCl₂[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; hydrogen; potassium tert-butylate / isopropyl alcohol / 40 h / 25 °C / 5171.62 Torr / Glovebox

2.1: Dess-Martin periodane / dichloromethane / 0.75 h / 20 °C

3.1: benzene / Irradiation

4.1: potassium tert-butylate / tetrahydrofuran / 0.75 h / 0 °C

4.2: 2 h / 3 - 20 °C

5.1: RuCl₂[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; hydrogen; potassium tert-butylate / isopropyl alcohol / 40 h / 25 °C / 5171.62 Torr / Glovebox

6.1: Dess-Martin periodane / dichloromethane / 0.75 h / 20 °C

With RuCl₂[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; potassium tert-butylate; hydrogen; Dess-Martin periodane; In tetrahydrofuran; dichloromethane; isopropyl alcohol; benzene; 2.1: |Dess-Martin Oxidation / 6.1: |Dess-Martin Oxidation;

DOI:10.1021/jo3023928

Reference yield:

(1R,2R)-1,2-diphenylpentan-1-ol (1032819-01-4) → (R)-α-octyl deoxybenzoin (1418731-62-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: Dess-Martin periodane / dichloromethane / 0.75 h / 20 °C

2.1: benzene / Irradiation

3.1: potassium tert-butylate / tetrahydrofuran / 0.75 h / 0 °C

3.2: 2 h / 3 - 20 °C

4.1: RuCl₂[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; hydrogen; potassium tert-butylate / isopropyl alcohol / 40 h / 25 °C / 5171.62 Torr / Glovebox

5.1: Dess-Martin periodane / dichloromethane / 0.75 h / 20 °C

With RuCl₂[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; potassium tert-butylate; hydrogen; Dess-Martin periodane; In tetrahydrofuran; dichloromethane; isopropyl alcohol; benzene; 1.1: |Dess-Martin Oxidation / 5.1: |Dess-Martin Oxidation;

DOI:10.1021/jo3023928

upstream raw materials:

1-Iodooctane

(1R,2R)-1,2-diphenylpentan-1-ol

C₂₀H₂₆O

C₂₂H₃₀O

Downstream raw materials:

1,2-diphenylpropan-1-one

(1R,2R)-1,2-diphenyl-propan-1-ol

C₂₀H₂₆O

1,2-diphenylpropan-1-one