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(1R,2R)-1,2-diphenylpentan-1-ol

Base Information
  • Chemical Name:(1R,2R)-1,2-diphenylpentan-1-ol
  • CAS No.:1032819-01-4
  • Molecular Formula:C17H20O
  • Molecular Weight:240.345
  • Hs Code.:
(1R,2R)-1,2-diphenylpentan-1-ol

Synonyms:(1R,2R)-1,2-diphenylpentan-1-ol

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Chemical Property of (1R,2R)-1,2-diphenylpentan-1-ol
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Technology Process of (1R,2R)-1,2-diphenylpentan-1-ol

There total 2 articles about (1R,2R)-1,2-diphenylpentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With RuCl2[(S)-xyl-SEGPHOS][(S)-DAIPEN]; potassium tert-butylate; hydrogen; In isopropyl alcohol; at 25 ℃; for 16h; under 5171.62 Torr; optical yield given as %ee; enantioselective reaction;
DOI:10.1021/ol800858c
Guidance literature:
Multi-step reaction with 2 steps
1.1: potassium tert-butylate / tetrahydrofuran / 0.75 h / 0 °C
1.2: 2 h / 3 - 20 °C
2.1: RuCl2[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; hydrogen; potassium tert-butylate / isopropyl alcohol / 40 h / 25 °C / 5171.62 Torr / Glovebox
With RuCl2[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; potassium tert-butylate; hydrogen; In tetrahydrofuran; isopropyl alcohol;
DOI:10.1021/jo3023928
Guidance literature:
Multi-step reaction with 7 steps
1.1: Dess-Martin periodane / dichloromethane / 0.75 h / 20 °C
2.1: benzene / Irradiation
3.1: potassium tert-butylate / tetrahydrofuran / 0.75 h / 0 °C
3.2: 2 h / 3 - 20 °C
4.1: RuCl2[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; hydrogen; potassium tert-butylate / isopropyl alcohol / 40 h / 25 °C / 5171.62 Torr / Glovebox
5.1: Dess-Martin periodane / dichloromethane / 0.75 h / 20 °C
6.1: dimethylsulfoxide-d6 / 0.5 h
7.1: aq. buffer / 0.25 h / Inert atmosphere; Irradiation
With RuCl2[(S)-(DM-SEGPHOS)][(S)-DAIPEN]; potassium tert-butylate; hydrogen; Dess-Martin periodane; In tetrahydrofuran; dimethylsulfoxide-d6; dichloromethane; isopropyl alcohol; benzene; 1.1: |Dess-Martin Oxidation / 5.1: |Dess-Martin Oxidation;
DOI:10.1021/jo3023928
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