2-methyl-5-nitro-N,4,6-triphenylnicotinamide

Base Information

• Chemical Name: 2-methyl-5-nitro-N,4,6-triphenylnicotinamide
• CAS No.: 900186-67-6
• Molecular Formula: C₂₅H₁₉N₃O₃
• Molecular Weight: 409.444
• Mol file: 900186-67-6.mol

Synonyms:2-methyl-5-nitro-N,4,6-triphenylnicotinamide

Chemical Property of 2-methyl-5-nitro-N,4,6-triphenylnicotinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-5-nitro-N,4,6-triphenylnicotinamide

There total 3 articles about 2-methyl-5-nitro-N,4,6-triphenylnicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-methyl-5-nitro-N,4,6-triphenyl-1,4-dihydropyridine-3-carboxamide (900186-60-9) → 2-methyl-5-nitro-N,4,6-triphenylnicotinamide (900186-67-6)

Guidance literature:

With acetic acid; sodium nitrite; at 60 - 70 ℃; for 1h;

DOI:10.1007/s10593-005-0214-4

Reference yield:

(Z)-2-nitro-1,3-diphenylprop-2-en-1-one (18315-85-0) → 2-methyl-5-nitro-N,4,6-triphenylnicotinamide (900186-67-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / acetic acid / 12 h / 20 °C

2: 80 percent / sodium nitrite / acetic acid / 1 h / 60 - 70 °C

With sodium nitrite; In acetic acid;

DOI:10.1134/S1070428006080173

Reference yield:

(E)-3-Amino-but-2-enoic acid phenylamide → 2-methyl-5-nitro-N,4,6-triphenylnicotinamide (900186-67-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / acetic acid / 12 h / 20 °C

2: 80 percent / sodium nitrite / acetic acid / 1 h / 60 - 70 °C

With sodium nitrite; In acetic acid;

DOI:10.1134/S1070428006080173

upstream raw materials:

2-methyl-5-nitro-N,4,6-triphenyl-1,4-dihydropyridine-3-carboxamide

(Z)-2-nitro-1,3-diphenylprop-2-en-1-one