3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

Base Information

Chemical Name:3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide
CAS No.:1429474-20-3
Molecular Formula:C₂₄H₂₈Cl₂N₂OS
Molecular Weight:463.471
Hs Code.:

Synonyms:3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

Suppliers and Price of 3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

There total 4 articles about 3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 111-26-2
hexan-1-amine

: C₁₈H₁₄Cl₃NOS

: 1429474-20-3
3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

Guidance literature:: With triethylamine; at 0 - 20 ℃;
DOI:10.1021/jm301735k

Reference yield:

: 1429474-18-9
3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)propanoic acid

: 1429474-20-3
3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / N,N-dimethyl-formamide; dichloromethane / 2 h / 0 °C / Inert atmosphere

2: triethylamine / 0 - 20 °C

With oxalyl dichloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm301735k

Reference yield:

: 1429474-16-7
methyl 3-(6-methyl-1H-indol-2-yl)propanoate

: 1429474-20-3
3-(3-((3,5-dichlorophenyl)thio)-6-methyl-1H-indol-2-yl)-N-hexylpropanamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 16 h / 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C

2.2: 24 h / 50 °C / Inert atmosphere

3.1: oxalyl dichloride / N,N-dimethyl-formamide; dichloromethane / 2 h / 0 °C / Inert atmosphere

4.1: triethylamine / 0 - 20 °C

With oxalyl dichloride; lithium hydroxide monohydrate; sodium hydride; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/jm301735k