1-Boc-4-(3-benzyl-2-oxopiperidin-1-ylMethyl)piperidine

Base Information

Chemical Name:1-Boc-4-(3-benzyl-2-oxopiperidin-1-ylMethyl)piperidine
CAS No.:340962-91-6
Molecular Formula:C₂₃H₃₄N₂O₃
Molecular Weight:386.535
Hs Code.:
Mol file:340962-91-6.mol

Synonyms:4-(3-benzyl-2-oxo-piperidin-1-ylmethyl)-piperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of 1-Boc-4-(3-benzyl-2-oxopiperidin-1-ylMethyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1-Boc-4-(3-benzyl-2-oxopiperidin-1-ylMethyl)piperidine

Chemical Property:

Vapor Pressure:0mmHg at 25°C

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-Boc-4-(3-benzyl-2-oxopiperidin-1-ylMethyl)piperidine

There total 4 articles about 1-Boc-4-(3-benzyl-2-oxopiperidin-1-ylMethyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6457-49-4
4-piperidinemethanol

: 340962-91-6
4-(3-benzyl-2-oxo-piperidin-1-ylmethyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / CH₂Cl₂

2: 100 percent / ClCOCOCl; DMSO; Et₃N / CH₂Cl₂

3: NaCNBH₃; CF₃CH₂OH; 3A sieves

With oxalyl dichloride; 2,2,2-trifluoroethanol; 3 A molecular sieve; sodium cyanoborohydride; dimethyl sulfoxide; triethylamine; In dichloromethane; 2: Swern oxidation;
DOI:10.1016/S0960-894X(00)00702-2

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 340962-91-6
4-(3-benzyl-2-oxo-piperidin-1-ylmethyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / CH₂Cl₂

2: 100 percent / ClCOCOCl; DMSO; Et₃N / CH₂Cl₂

3: NaCNBH₃; CF₃CH₂OH; 3A sieves

With oxalyl dichloride; 2,2,2-trifluoroethanol; 3 A molecular sieve; sodium cyanoborohydride; dimethyl sulfoxide; triethylamine; In dichloromethane; 2: Swern oxidation;
DOI:10.1016/S0960-894X(00)00702-2

Reference yield:

: 123855-51-6
tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate

: 340962-91-6
4-(3-benzyl-2-oxo-piperidin-1-ylmethyl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / ClCOCOCl; DMSO; Et₃N / CH₂Cl₂

2: NaCNBH₃; CF₃CH₂OH; 3A sieves

With oxalyl dichloride; 2,2,2-trifluoroethanol; 3 A molecular sieve; sodium cyanoborohydride; dimethyl sulfoxide; triethylamine; In dichloromethane; 1: Swern oxidation;
DOI:10.1016/S0960-894X(00)00702-2