6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

Base Information

Chemical Name:6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide
CAS No.:1315377-13-9
Molecular Formula:C₅₁H₅₈ClN₅O₂Si
Molecular Weight:836.592
Hs Code.:

6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

Synonyms:6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

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Chemical Property of 6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

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Technology Process of 6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

There total 7 articles about 6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 1315377-11-7
6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)hexanoic acid

: 75867-39-9
4-trimethylsilylethynyl aniline

: 1315377-13-9
6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

Guidance literature:: 6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)hexanoic acid; 4-trimethylsilylethynyl aniline; In tetrahydrofuran; for 0.166667h;

With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In tetrahydrofuran; for 24h;

Reference yield:

: 1640-39-7
2,3,3-trimethylindoleniune

: 1315377-13-9
6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: nitromethane / 20 h / Inert atmosphere; Reflux

2.1: pyridine / ethanol / Inert atmosphere; Reflux

3.1: tetrahydrofuran / 0.17 h

3.2: 24 h

With pyridine; In tetrahydrofuran; nitromethane; ethanol;

Reference yield:

: 4224-70-8
6-bromohexanoic acid

: 1315377-13-9
6-((E)-2-((E)-2-(5-tert-butyl-2-chloro-3-((E)-2-(4-cyano-5-(dicyanomethylene)-2,2-dimethyl-2,5-dihydrofuran-3-yl)vinyl)cyclohex-2-enylidene)ethylidene)-3,3-dimethylindolin-1-yl)-N-(4-((trimethylsilyl)ethynyl)phenyl)hexanamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: nitromethane / 20 h / Inert atmosphere; Reflux

2.1: pyridine / ethanol / Inert atmosphere; Reflux

3.1: tetrahydrofuran / 0.17 h

3.2: 24 h

With pyridine; In tetrahydrofuran; nitromethane; ethanol;