6-(hex-5-yn-1-yloxy)hex-1-yne

Base Information

• Chemical Name: 6-(hex-5-yn-1-yloxy)hex-1-yne
• CAS No.: 4641-77-4
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.274
• Mol file: 4641-77-4.mol

Synonyms:6-(hex-5-yn-1-yloxy)hex-1-yne

Chemical Property of 6-(hex-5-yn-1-yloxy)hex-1-yne

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 6-(hex-5-yn-1-yloxy)hex-1-yne

There total 1 articles about 6-(hex-5-yn-1-yloxy)hex-1-yne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

5-hexynyl p-toluenesulfonate (76911-01-8) → 6-fluorohex-1-yne (373-16-0) + 6-(hex-5-yn-1-yloxy)hex-1-yne (4641-77-4)

Guidance literature:

With potassium fluoride; In tetrahydrofuran; at 50 ℃; for 17h;

DOI:10.1039/c5ob02258d

Reference yield: 60.0%

6-(hex-5-yn-1-yloxy)hex-1-yne (4641-77-4) + 1-phenyl-2-hydroxyethanone (582-24-1) → C20H22O3

Guidance literature:

1-phenyl-2-hydroxyethanone; With copper(I) thiophene-2-carboxylate; oxygen; In toluene; at 90 ℃; for 2h; Schlenk technique;

6-(hex-5-yn-1-yloxy)hex-1-yne; In toluene; for 12h; Schlenk technique; Heating;

DOI:10.1021/ol502298a

Reference yield: 31.7%

6-(hex-5-yn-1-yloxy)hex-1-yne (4641-77-4) + N-succinimidyl 3-(azidomethyl)-5-((1,2-bis(tert-butoxycarbonyl)guanidino)methyl)benzoate → C36H49N7O9

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; at 80 ℃; for 0.5h; Sealed tube;

DOI:10.1039/c5ob02258d

upstream raw materials:

5-hexynyl p-toluenesulfonate

Downstream raw materials:

2-(5-methoxy-pent-1-yn-1-yl)-benzenesulfonamide