Technology Process of 5-O-(tert-butyldiphenylsilyl)-3-O-tetradecanoyl-2-deoxy-L-ribonolactone
There total 7 articles about 5-O-(tert-butyldiphenylsilyl)-3-O-tetradecanoyl-2-deoxy-L-ribonolactone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridine; dmap;
In
dichloromethane;
for 20h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 95 percent / dimethylformamide
2: 98 percent / 10percent aq. HCl / tetrahydrofuran / 4 h / Ambient temperature
3: 86 percent / DMAP, pyridine / CH2Cl2 / 24 h / Ambient temperature
4: 79 percent / CH3I, CaCO3, water / acetonitrile; H2O / 20 h / 47 °C
5: 91 percent / tetrapropylammonium perruthenate, 4-methylmorpholine N-oxide, 4 A sieves / CH2Cl2 / 4 h / Ambient temperature
6: 87 percent / H2, acetic acid / 10percent Pd/C / acetone; methanol / 72 h / 2585.7 Torr / Ambient temperature
7: 97 percent / pyridine, DMAP / CH2Cl2 / 20 h / Ambient temperature
With
pyridine; hydrogenchloride; dmap; tetrapropylammonium perruthennate; 4 A molecular sieve; water; hydrogen; acetic acid; 4-methylmorpholine N-oxide; calcium carbonate; methyl iodide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 98 percent / 10percent aq. HCl / tetrahydrofuran / 4 h / Ambient temperature
2: 86 percent / DMAP, pyridine / CH2Cl2 / 24 h / Ambient temperature
3: 79 percent / CH3I, CaCO3, water / acetonitrile; H2O / 20 h / 47 °C
4: 91 percent / tetrapropylammonium perruthenate, 4-methylmorpholine N-oxide, 4 A sieves / CH2Cl2 / 4 h / Ambient temperature
5: 87 percent / H2, acetic acid / 10percent Pd/C / acetone; methanol / 72 h / 2585.7 Torr / Ambient temperature
6: 97 percent / pyridine, DMAP / CH2Cl2 / 20 h / Ambient temperature
With
pyridine; hydrogenchloride; dmap; tetrapropylammonium perruthennate; 4 A molecular sieve; water; hydrogen; acetic acid; 4-methylmorpholine N-oxide; calcium carbonate; methyl iodide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane; water; acetone; acetonitrile;
