8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine

Base Information

• Chemical Name: 8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine
• CAS No.: 1138038-51-3
• Molecular Formula: C₄₅H₅₉N₅O₄
• Molecular Weight: 733.995
• Mol file: 1138038-51-3.mol

Synonyms:8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine

Chemical Property of 8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine

There total 1 articles about 8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)acetic acid (351185-23-4) + 3,5-Bis[3,5-di(tert-butyl)benzyloxy]benzylamine → 8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine (1138038-51-3)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.1039/b817733n

Reference yield:

8-{[3,5-bis(3,5-di-tert-butylbenzyloxy)benzylcarbamoyl]methyl}-7-deazaguanine (1138038-51-3) + 2-naphthaloyl chloride (2243-83-6) → C56H65N5O5 (1138038-28-4)

Guidance literature:

With pyridine; at 65 ℃; for 18h;

DOI:10.1039/b817733n

upstream raw materials:

2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)acetic acid

Downstream raw materials:

C₅₆H₆₅N₅O₅