Technology Process of C22H30N2O3
There total 5 articles about C22H30N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
tert-butyl 2-chloro-5-pyridinecarboxylate; C12H19NO*ClH;
With
toluene-4-sulfonic acid;
In
1,4-dioxane;
at 100 ℃;
for 22h;
Reflux;
With
sodium hydrogencarbonate;
In
1,4-dioxane; water;
Saturated solution;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1.5 h
2.1: hydrogenchloride; hydrogen / palladium on activated charcoal / methanol; water / 1.5 h / 20 °C
3.1: toluene-4-sulfonic acid / 1,4-dioxane / 22 h / 100 °C / Reflux
3.2: Saturated solution
With
hydrogenchloride; hydrogen; potassium carbonate; toluene-4-sulfonic acid; potassium iodide;
palladium on activated charcoal;
In
1,4-dioxane; methanol; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sulfuric acid; water; sodium nitrite / 0 - 5 °C
2.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1.5 h
3.1: hydrogenchloride; hydrogen / palladium on activated charcoal / methanol; water / 1.5 h / 20 °C
4.1: toluene-4-sulfonic acid / 1,4-dioxane / 22 h / 100 °C / Reflux
4.2: Saturated solution
With
hydrogenchloride; sulfuric acid; water; hydrogen; potassium carbonate; toluene-4-sulfonic acid; potassium iodide; sodium nitrite;
palladium on activated charcoal;
In
1,4-dioxane; methanol; water; N,N-dimethyl-formamide;
