115309-57-4

Basic information

• Product Name: 6-Chloronicotinic acid tert-butyl ester
• Synonyms: 6-Chloronicotinic acid tert-butyl ester;tert-butyl 2-chloro-5-pyridinecarboxylate;tert-Butyl 6-chloronicotinate;tert-butyl 6-chloropyridine-3-carboxylate
• CAS NO: 115309-57-4
• Molecular Formula: C₁₀H₁₂ClNO₂
• Molecular Weight: 213.66
• Mol File: 115309-57-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 53-54 °C
• Boiling Point: 270.7±20.0 °C(Predicted)
• Appearance: /
• Density: 1.173±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.13±0.10(Predicted)
• CAS DataBase Reference: 6-Chloronicotinic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloronicotinic acid tert-butyl ester(115309-57-4)
• EPA Substance Registry System: 6-Chloronicotinic acid tert-butyl ester(115309-57-4)

Safety Data

• Hazardous Substances Data: 115309-57-4(Hazardous Substances Data)

Usage

General Description

6-Chloronicotinic acid tert-butyl ester is a chemical compound with the molecular formula C11H13ClNO2. It is a derivative of nicotinic acid and belongs to the class of organic compounds known as pyridine carboxylic acids. 6-Chloronicotinic acid tert-butyl ester is a white solid with a molecular weight of 235.68 g/mol. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The tert-butyl ester group in the molecule provides stability and protection to the carboxylic acid functionality, making it a valuable building block in organic synthesis. Additionally, the chlorine atom in its structure introduces unique reactivity and pharmacological properties, making it an important compound for the development of novel drugs and biologically active molecules.

Upstream product

• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 24424-99-5 di-tert-butyl dicarbonate 
• 75-65-0 tert-butyl alcohol 
• 67098-46-8 O-tert-butyl-N,N-diisopropyl-isourea 
• 58757-38-3 6-Chloronicotinoyl chloride 

Downstream Products

• 1055233-55-0 C₂₂H₃₀N₂O₃ 
• 163213-19-2 tert-butyl 6-hydrazinylpyridine-3-carboxylate 
• 893397-44-9 BMS-688521 
• 186797-49-9 tert-butyl2-[N-(2-benzyloxy-5-bromophenethyl)-amino]-5-pyridinecarboxylate 
• 893397-49-4 tert-butyl 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinate 

Relevant articles and documents

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