C₄₆H₅₃ClN₈O₇

Base Information

• Chemical Name: C₄₆H₅₃ClN₈O₇
• CAS No.: 1049812-10-3
• Molecular Formula: C₄₆H₅₃ClN₈O₇
• Molecular Weight: 865.429
• Mol file: 1049812-10-3.mol

Synonyms:C₄₆H₅₃ClN₈O₇

Chemical Property of C₄₆H₅₃ClN₈O₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₆H₅₃ClN₈O₇

There total 5 articles about C₄₆H₅₃ClN₈O₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C61H63ClN8O9 (1049812-04-5) → C46H53ClN8O7 (1049812-10-3)

Guidance literature:

With piperidine; In N,N-dimethyl-formamide; for 1h;

Reference yield:

tert-butyl 4-aminobenzoate (18144-47-3) → C46H53ClN8O7 (1049812-10-3)

Guidance literature:

Multi-step reaction with 5 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / copper dichloride / tetrahydrofuran; N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / dichloromethane / 0.33 h

3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C

4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 2 h / 20 °C

5: piperidine / N,N-dimethyl-formamide / 1 h

With piperidine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; copper dichloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

Fmoc-Lys(tert-butoxycarbonyl) (71989-26-9) → C46H53ClN8O7 (1049812-10-3)

Guidance literature:

Multi-step reaction with 5 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / copper dichloride / tetrahydrofuran; N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / dichloromethane / 0.33 h

3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C

4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 2 h / 20 °C

5: piperidine / N,N-dimethyl-formamide / 1 h

With piperidine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; copper dichloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

C₆₁H₆₃ClN₈O₉

C₂₈H₂₉N₃O₅

C₃₃H₃₇N₃O₇

tert-butyl 4-aminobenzoate

Downstream raw materials:

C₅₆H₆₄ClN₉O₁₀

C₅₁H₅₆ClN₉O₈