3-allyloxy-2-methoxy-6-phenylnaphthalene

Base Information

• Chemical Name: 3-allyloxy-2-methoxy-6-phenylnaphthalene
• CAS No.: 1437324-83-8
• Molecular Formula: C₂₀H₁₈O₂
• Molecular Weight: 290.362
• Mol file: 1437324-83-8.mol

Synonyms:3-allyloxy-2-methoxy-6-phenylnaphthalene

Chemical Property of 3-allyloxy-2-methoxy-6-phenylnaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-allyloxy-2-methoxy-6-phenylnaphthalene

There total 3 articles about 3-allyloxy-2-methoxy-6-phenylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-allyloxy-4-methoxy-2-(3-phenylallyl)benzaldehyde → 3-allyloxy-2-methoxy-6-phenylnaphthalene (1437324-83-8) + 1-allyl-3-methoxy-7-phenylnaphthalen-2-ol

Guidance literature:

In decalin; for 20h; Reflux;

DOI:10.1055/s-0037-1610175

Reference yield:

(E)-1-cinnamylsulfonyl-4-methylbenzene (20605-48-5) + 5-allyloxy-4-methoxy-2-(3-phenylallyl)benzaldehyde + C20H20O3 (1437324-81-6) → 3-allyloxy-2-methoxy-6-phenylnaphthalene (1437324-83-8) + 1-allyloxy-2-methoxy-5-phenylnaphthalene (1437324-85-0)

Guidance literature:

(E)-1-cinnamylsulfonyl-4-methylbenzene; With sodium hydride; In toluene; at 20 ℃; for 0.166667h; Inert atmosphere;

5-allyloxy-4-methoxy-2-(3-phenylallyl)benzaldehyde; C₂₀H₂₀O₃; In toluene; at 20 ℃; for 6h; Reflux; Inert atmosphere;

DOI:10.1021/ol401152w

Reference yield:

sodium 4-methylbenzenesulfinate (824-79-3) → 3-allyloxy-2-methoxy-6-phenylnaphthalene (1437324-83-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: water; 1,4-dioxane / 6 h / 20 °C / Reflux; Inert atmosphere

2.1: sodium hydride / toluene / 0.17 h / 20 °C / Inert atmosphere

2.2: 6 h / 20 °C / Reflux; Inert atmosphere

With sodium hydride; In 1,4-dioxane; water; toluene;

DOI:10.1021/ol401152w

upstream raw materials:

(E)-1-cinnamylsulfonyl-4-methylbenzene

C₂₀H₂₀O₃

sodium 4-methylbenzenesulfinate

Refernces

• 1、 Chang, Meng-Yang,Wu, Ming-Hao,Chen, Yeh-Long. "One-pot synthesis of substituted tetrahydrocyclobuta[a]naphthalenes by domino aldol condensation/olefin migration/electrocyclization". supporting information. p. 2822 - 2825. Retrieved 2013/07/26.