8-Chlorohypoxanthine

Base Information

• Chemical Name: 8-Chlorohypoxanthine
• CAS No.: 22712-29-4
• Molecular Formula: C5H3ClN4O
• Molecular Weight: 170.56
• Mol file: 22712-29-4.mol

Synonyms:8-Chloro-5,9-dihydropurin-6-one;8-Chloro-3,7-dihydropurin-6-one;

Chemical Property of 8-Chlorohypoxanthine

Chemical Property:

• Vapor Pressure: 0.00356mmHg at 25°C
• Refractive Index: 1.91
• Boiling Point: 281.5 °C at 760 mmHg
• Flash Point: 124 °C
• PSA: 74.43000
• Density: 2.09 g/cm³
• LogP: 0.29960

Purity/Quality:

99% ^*data from raw suppliers

8-CHLOROHYPOXANTHINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-Chlorohypoxanthine

There total 5 articles about 8-Chlorohypoxanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6,8-dichloro-7(9)H-purine (19916-15-5) → 8-chlorohypoxanthine (22712-29-4)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01557a051

Reference yield:

diceto-6,8 purine (13231-00-0) → 8-chlorohypoxanthine (22712-29-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-diethyl-aniline; POCl₃

2: aqueous KOH

With potassium hydroxide; N,N-diethylaniline; trichlorophosphate;

DOI:10.1021/ja01557a051

Reference yield:

8-chloroadenine (28128-28-1) → 8-chlorohypoxanthine (22712-29-4)

Guidance literature:

With cis-nitrous acid;

DOI:10.1021/ja01557a051

upstream raw materials:

8-chloroadenine

6,8-dichloro-7(9)H-purine

diceto-6,8 purine